Human B7-1/CD80 Antibody | R&D Systems MAB140 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-1/CD80 Antibody

catalog :

MAB140

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

37711

reactivity :

human

application :

immunohistochemistry, neutralization, flow cytometry, blocking or activating experiments

citations: 10

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; 1 ug/ml; loading ...; fig 3a	Li R, Rezk A, Li H, Gommerman J, Prat A, Bar Or A. Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses. J Immunol. 2017;198:3245-3254 pubmed publisher
	Minamikawa S, Nozu K, Maeta S, Yamamura T, Nakanishi K, Fujimura J, et al. The utility of urinary CD80 as a diagnostic marker in patients with renal diseases. Sci Rep. 2018;8:17322 pubmed publisher
	Li J, Xu S, Zhao Y, Yu S, Ge L, Xu B. Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord. Mol Med Rep. 2018;18:4969-4977 pubmed publisher
	He S, Wu C, Xiao J, Li D, Sun Z, Li M. Endothelial extracellular vesicles modulate the macrophage phenotype: Potential implications in atherosclerosis. Scand J Immunol. 2018;87:e12648 pubmed publisher
	Lee S, Baek S, Paik J, Kim S, Na K, Chae D, et al. Tubular B7-1 expression parallels proteinuria levels, but not clinical outcomes in adult minimal change disease patients. Sci Rep. 2017;7:41859 pubmed publisher
	Luo X, Liu X, Tang J, Yang W, Ni Z, Chen Q, et al. Autoantibodies against CD80 in patients with COPD. Clin Transl Immunology. 2016;5:e103 pubmed
	Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, et al. Tumor-activated TCR??? T cells from gastric cancer patients induce the antitumor immune response of TCR??? T cells via their antigen-presenting cell-like effects. J Immunol Res. 2014;2014:593562 pubmed publisher
	Ribot J, deBarros A, Mancio Silva L, Pamplona A, Silva Santos B. B7-CD28 costimulatory signals control the survival and proliferation of murine and human ?? T cells via IL-2 production. J Immunol. 2012;189:1202-8 pubmed publisher
	Weissmüller S, Semmler L, Kalinke U, Christians S, Muller Berghaus J, Waibler Z. ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood. 2012;119:6268-77 pubmed publisher
	Kosaka K, Yashiro M, Sakate Y, Hirakawa K. A synergistic antitumor effect of interleukin-2 addition with CD80 immunogene therapy for peritoneal metastasis of gastric carcinoma. Dig Dis Sci. 2007;52:1946-53 pubmed

product information

brand :

R&D Systems

master code :

MAB140

SKU :

MAB140-100

product name :

Human B7-1/CD80 Antibody

description :

The Human B7-1/CD80 Antibody from R&D Systems is a mouse monoclonal antibody to B7-1/CD80. This antibody reacts with human. The Human B7-1/CD80 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready, Dual RNAscope ISH-IHC, ELISA Capture (Matched Antibody Pair).

target :

B7-1/CD80

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

37711

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human B7-1/CD80, Val35-Asn242 (predicted), Accession # P33681

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human B7-1/CD80 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant human (rh) B7-2, recombinant mouse (rm) B7-1, rmB7-2, rhB7-H1, rhB7-H2, rhB7-H3 or rmPD-L2 is observed.

gene symbol :

CD80

details of functionality :

ActivityAssaywCitation not found None None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB140

accessionNumbers :

P33681

applications :

Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready, Dual RNAscope ISH-IHC, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

Activation B7-1 antigen, B7, B71, BB1, CD28LG1, CD28LGB7-1 antigen), CD80, CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.