product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse DLL4 Antibody
catalog :
MAB1389
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
207822
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 10
Reference
Leach A, Smyth P, Ferguson L, Steven J, Greene M, Branco C, et al. Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature. Nanoscale. 2020;12:14751-14763 pubmed publisher
Wei S, Huang Y, Hsieh M, Lin Y, Shyu W, Chen H, et al. Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Cell Death Dis. 2020;11:307 pubmed publisher
Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
Verma M, Asakura Y, Murakonda B, Pengo T, Latroche C, Chazaud B, et al. Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling. Cell Stem Cell. 2018;23:530-543.e9 pubmed publisher
Sacilotto N, Chouliaras K, Nikitenko L, Lu Y, Fritzsche M, Wallace M, et al. MEF2 transcription factors are key regulators of sprouting angiogenesis. Genes Dev. 2016;30:2297-2309 pubmed
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed publisher
Wälchli T, Mateos J, Weinman O, Babic D, Regli L, Hoerstrup S, et al. Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain. Nat Protoc. 2015;10:53-74 pubmed publisher
Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Küchler A, WEISS M, et al. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012;181:1099-111 pubmed publisher
Liu R, Li X, Tulpule A, Zhou Y, Scehnet J, Zhang S, et al. KSHV-induced notch components render endothelial and mural cell characteristics and cell survival. Blood. 2010;115:887-95 pubmed publisher
Skokos D, Nussenzweig M. CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med. 2007;204:1525-31 pubmed
product information
brand :
R&D Systems
master code :
MAB1389
SKU :
MAB1389
product name :
Human/Mouse DLL4 Antibody
unit size :
500 ug (also 25 ug)
seo description :
The Human/Mouse DLL4 Antibody from R&D Systems is a rat monoclonal antibody to DLL4. This antibody reacts with human,mouse. The Human/Mouse DLL4 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
DLL4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
207822
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Immunohistochemistry 5-25 ug/mL
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse DLL4, Ser28-Pro525, Accession # Q9JI71
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse DLL4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows 100% cross-reactivity with recombinant human DLL4.
gene symbol :
DLL4
top caption :
DLL4 antibody in Mouse Embryonic Heart by Immunohistochemistry (IHC-Fr).
accessionNumbers :
Q9JI71
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
559 USD
alt names :
delta 4, Delta 4 precursor, delta ligand 4, delta4, delta-like 4 (Drosophila), delta-like 4 homolog, delta-like 4 homolog (Drosophila), delta-like 4 protein, delta-like protein 4, Drosophila Delta homolog 4, hdelta2, MGC126344, notch ligand delta-2, notch ligand DLL4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.