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company name :
R&D Systems
product type :
antibody
product name :
NKG2C/CD159c Antibody
catalog :
MAB138-100
quantity :
100 ug (also 25 ug)
price :
453 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
134591
reactivity :
human
application :
flow cytometry
more info or order :
citations: 23
Reference
Wagstaffe H, Anzala O, Kibuuka H, Anywaine Z, Sirima S, Thi xe9 baut R, et al. NK Cell Subset Redistribution and Antibody Dependent Activation after Ebola Vaccination in Africans. Vaccines (Basel). 2022;10: pubmed publisher
Jiang L, Fei H, Jin X, Liu X, Yang C, Li C, et al. Extracellular Vesicle-Mediated Secretion of HLA-E by Trophoblasts Maintains Pregnancy by Regulating the Metabolism of Decidual NK Cells. Int J Biol Sci. 2021;17:4377-4395 pubmed publisher
Wiedemann G, Santosa E, Grassmann S, Sheppard S, Le Luduec J, Adams N, et al. Deconvoluting global cytokine signaling networks in natural killer cells. Nat Immunol. 2021;22:627-638 pubmed publisher
Brownlie D, Scharenberg M, Mold J, Hård J, Kekäläinen E, Buggert M, et al. Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Makanga D, Guillaume T, Willem C, Legrand N, Gagne K, Cesbron A, et al. Posttransplant Cyclophosphamide and Antithymocyte Globulin versus Posttransplant Cyclophosphamide as Graft-versus-Host Disease Prophylaxis for Peripheral Blood Stem Cell Haploidentical Transplants: Comparison of T Cell and NK Effector Reconstitution. J Immunol. 2020;205:1441-1448 pubmed publisher
Comeau E, Holder K, Fudge N, Grant M. Cytomegalovirus-Driven Adaption of Natural Killer Cells in NKG2Cnull Human Immunodeficiency Virus-Infected Individuals. Viruses. 2019;11: pubmed publisher
Muller Durovic B, Grählert J, Devine O, Akbar A, Hess C. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging (Albany NY). 2019;11:724-740 pubmed publisher
Wang E, Pjechova M, Nightingale K, Vlahava V, Patel M, Růcková E, et al. Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proc Natl Acad Sci U S A. 2018;115:4998-5003 pubmed publisher
Martrus G, Kautz T, Lunemann S, Richert L, Glau L, Salzberger W, et al. Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells. PLoS ONE. 2017;12:e0182532 pubmed publisher
Cichocki F, Valamehr B, Bjordahl R, Zhang B, Rezner B, Rogers P, et al. GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity. Cancer Res. 2017;77:5664-5675 pubmed publisher
Cooper A, Lill G, Shaw K, Carbonaro Sarracino D, Davila A, Sokolic R, et al. Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients. Blood. 2017;129:2624-2635 pubmed publisher
Riou R, Bressollette Bodin C, Boutoille D, Gagne K, Rodallec A, Lefebvre M, et al. Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses. J Virol. 2017;91: pubmed publisher
Huijskens M, Walczak M, Sarkar S, Atrafi F, Senden Gijsbers B, Tilanus M, et al. Ascorbic acid promotes proliferation of natural killer cell populations in culture systems applicable for natural killer cell therapy. Cytotherapy. 2015;17:613-20 pubmed publisher
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le V, et al. MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog. 2014;10:e1003963 pubmed publisher
Saghafian Hedengren S, Sohlberg E, Theorell J, Carvalho Queiroz C, Nagy N, Persson J, et al. Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells. J Virol. 2013;87:13446-55 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
Dupuy S, Lambert M, Zucman D, Choukem S, Tognarelli S, Pagès C, et al. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog. 2012;8:e1002486 pubmed publisher
Angelini D, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, et al. NKG2A inhibits NKG2C effector functions of ?? T cells: implications in health and disease. J Leukoc Biol. 2011;89:75-84 pubmed publisher
Yu J, Mao H, Wei M, Hughes T, Zhang J, Park I, et al. CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood. 2010;115:274-81 pubmed publisher
Beziat V, Nguyen S, Lapusan S, Hervier B, Dhedin N, Bories D, et al. Fully functional NK cells after unrelated cord blood transplantation. Leukemia. 2009;23:721-8 pubmed publisher
Dutertre C, Bonnin Gélizé E, Pulford K, Bourel D, Fridman W, Teillaud J. A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function. J Leukoc Biol. 2008;84:1511-20 pubmed publisher
de Matos C, Berg L, Michaelsson J, Fellander Tsai L, Kärre K, Soderstrom K. Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion. Immunology. 2007;122:291-301 pubmed
product information
brand :
R&D Systems
master code :
MAB138
SKU :
MAB138-100
product name :
NKG2C/CD159c Antibody
description :
The Human NKG2C/CD159c Antibody from R&D Systems is a mouse monoclonal antibody to NKG2C/CD159c/KLRC2. This antibody reacts with human. The Human NKG2C/CD159c Antibody has been validated for the following applications: Flow Cytometry, CyTOF-reported.
target :
NKG2C/CD159c
category :
Primary Antibodies
sizes available :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
134591
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry
gene symbol :
KLRC2
applications :
Flow Cytometry, CyTOF-reported
USD :
453 USD
alt names :
CD159 antigen-like family member C, CD159c, CD159c antigen, killer cell lectin-like receptor subfamily C, member 2, KLRC2, MGC138244, NK cell receptor C, NKG2-C, NKG2-C type II integral membrane protein, NKG2CNKG2-C-activating NK receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.