product summary
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company name :
R&D Systems
product type :
antibody
product name :
alpha-Fetoprotein/AFP Antibody
catalog :
MAB1369
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
189506
reactivity :
human, chimpanzee
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 21
Reference
Karvas R, Zemke J, Ali S, Upton E, Sane E, Fischer L, et al. 3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages. Cell Stem Cell. 2023;30:1148-1165.e7 pubmed publisher
Lotila J, Hyv xe4 rinen T, Skottman H, Airas L, Narkilahti S, Hagman S. Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient. Stem Cell Res. 2022;63:102865 pubmed publisher
Banal C, Lefort N. Generation and characterization of IMAGINi013-A, an induced pluripotent stem cell line generated from a healthy donor. Stem Cell Res. 2022;61:102755 pubmed publisher
Choi N, Lee Y, Park Y, Ko K, Park B, Koh Y. Establishment of an integration-free human induced pluripotent stem cell line (TJCi001-A) from normal bone marrow-derived mesenchymal stem cells. Stem Cell Res. 2021;55:102484 pubmed publisher
Di Buduo C, Laurent P, Zaninetti C, Lordier L, Soprano P, Ntai A, et al. Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients. elife. 2021;10: pubmed publisher
Banal C, Quelennec E, Bertani Torres W, Gacem N, Amiel J, Marlin S, et al. Generation of an iPSC line (IMAGINi022-A) from a patient carrying a SOX10 missense mutation and presenting with deafness, depigmentation and progressive neurological impairment. Stem Cell Res. 2020;48:101936 pubmed publisher
Menara G, Lefort N, Antignac C, Mollet G. Generation of an induced pluripotent stem cell (iPSC) line (IMAGINi007) from a patient with steroid-resistant nephrotic syndrome carrying the homozygous p.R138Q mutation in the podocin-encoding NPHS2 gene. Stem Cell Res. 2020;46:101878 pubmed publisher
Kitajima R, Nakai R, Imamura T, Kameda T, Kozuka D, Hirai H, et al. Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells. Stem Cell Res. 2020;44:101749 pubmed publisher
Shafa M, Walsh T, Panchalingam K, Richardson T, Menendez L, Tian X, et al. Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2019;21: pubmed publisher
Kaur S, Abu Shahba A, Paananen R, Hongisto H, Hiidenmaa H, Skottman H, et al. Small non-coding RNA landscape of extracellular vesicles from human stem cells. Sci Rep. 2018;8:15503 pubmed publisher
Barnes J, Salas F, Mokhtari R, Dolstra H, Pedrosa E, Lachman H. Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells. Mol Autism. 2018;9:44 pubmed publisher
Nakai R, Ohnuki M, Kuroki K, Ito H, Hirai H, Kitajima R, et al. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata). Sci Rep. 2018;8:12187 pubmed publisher
Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne). 2018;5:69 pubmed publisher
Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, et al. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells. Nat Commun. 2016;7:13602 pubmed publisher
Ahmadian Baghbaderani B, Tian X, Scotty Cadet J, Shah K, Walde A, Tran H, et al. A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells. PLoS ONE. 2016;11:e0161229 pubmed publisher
Baghbaderani B, Syama A, Sivapatham R, Pei Y, Mukherjee O, Fellner T, et al. Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications. Stem Cell Rev. 2016;12:394-420 pubmed publisher
Wren M, Zhao J, Liu C, Murray M, Atagi Y, Davis M, et al. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells. Mol Neurodegener. 2015;10:46 pubmed publisher
Onuma Y, Higuchi K, Aiki Y, Shu Y, Asada M, Asashima M, et al. A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture. PLoS ONE. 2015;10:e0118931 pubmed publisher
Valli A, Rosner M, Fuchs C, Siegel N, Bishop C, Dolznig H, et al. Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Oncogene. 2010;29:966-77 pubmed publisher
Vallier L, Reynolds D, Pedersen R. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev Biol. 2004;275:403-21 pubmed
Tramontini N, Huber C, Liu Bryan R, Terkeltaub R, Kilgore K. Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum. 2004;50:2633-9 pubmed
image
image 1 :
R&D Systems MAB1369 image 1
a-Fetoprotein/AFP antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC).
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
MAB1369
SKU :
MAB1369
product name :
alpha-Fetoprotein/AFP Antibody
description :
The Human alpha-Fetoprotein/AFP Antibody from R&D Systems is a mouse monoclonal antibody to alpha-Fetoprotein/AFP. This antibody reacts with human,primate - pan troglodytes (chimpanzee). The Human alpha-Fetoprotein/AFP Antibody has been validated for the following applications: Intracellular Staining by Flow Cytometry,CyTOF-reported,Knockout Validated,Differentiation,Flow Cytometry,Immunohistochemistry,Western Blot,Immunocytochemistry.
target :
alpha-Fetoprotein/AFP
unit size :
100 ug (also 25 ug)
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
189506
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human umbilical cord serum-derived alpha -Fetoprotein
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Pan troglodytes (Chimpanzee)
specificity :
Detects human alpha -Fetoprotein in direct ELISAs.
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
gene symbol :
AFP
Antibody validation :
Knockout/Knockdown
applications :
Intracellular Staining by Flow Cytometry,CyTOF-reported,Knockout Validated,Differentiation,Flow Cytometry,Immunohistochemistry,Western Blot,Immunocytochemistry
product keywords :
MAB1369, hAFP MAb Cl 189506, Mouse Anti-Human alpha-Fetoprotein/AFP Monoclonal Antibody, Anti-alpha-Fetoprotein, Anti-AFP, Mouse Anti Human alpha-Fetoprotein/AFP Monoclonal Antibody, Anti-halpha-Fetoprotein, alphaFetoprotein, -Fetoprotein, alfa-Fetoprotein, a-Fetoprotein, AFP, alpha Fetoprotein, Down Syndrome, Down's Syndrome
USD :
459
USD 2025 :
489 USD
alt names :
AFP, Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, DSCAM2, FETA, HP, HPAFP
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.