BAFF/BLyS/TNFSF13B Antibody | R&D Systems MAB1357-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

BAFF/BLyS/TNFSF13B Antibody

catalog :

MAB1357-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

121808

reactivity :

human, mouse

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Reference
Pham G, Wang L, Mathis K. Pharmacological potentiation of the efferent vagus nerve attenuates blood pressure and renal injury in a murine model of systemic lupus erythematosus. Am J Physiol Regul Integr Comp Physiol. 2018;315:R1261-R1271 pubmed publisher
Matsushita T, Kobayashi T, Mizumaki K, Kano M, Sawada T, Tennichi M, et al. BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance. Sci Adv. 2018;4:eaas9944 pubmed publisher
de Riva A, Wallberg M, Ronchi F, Coulson R, Sage A, Thorne L, et al. Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment. PLoS ONE. 2017;12:e0181964 pubmed publisher
Cremasco V, Woodruff M, Onder L, Cupovic J, Nieves Bonilla J, Schildberg F, et al. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol. 2014;15:973-81 pubmed publisher
Yasuda K, Watkins A, Kochar G, Wilson G, Laskow B, Richez C, et al. Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2. PLoS ONE. 2014;9:e103478 pubmed publisher
Giordano D, Draves K, Li C, Hohl T, Clark E. Nitric oxide regulates BAFF expression and T cell-independent antibody responses. J Immunol. 2014;193:1110-20 pubmed publisher
Kanagavelu S, Termini J, Gupta S, Raffa F, Fuller K, Rivas Y, et al. HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity. PLoS ONE. 2014;9:e90100 pubmed publisher
Goenka R, Matthews A, Zhang B, O Neill P, Scholz J, Migone T, et al. Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med. 2014;211:45-56 pubmed publisher
Scapini P, Hu Y, Chu C, Migone T, DeFranco A, Cassatella M, et al. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. J Exp Med. 2010;207:1757-73 pubmed publisher
Parameswaran R, Ben David H, Sharabi A, Zinger H, Mozes E. B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus. Clin Immunol. 2009;131:223-32 pubmed publisher
Wan S, Zhou Z, Duan B, Morel L. Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum. 2008;58:1741-50 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

MAB1357

SKU :

MAB1357-100

product name :

BAFF/BLyS/TNFSF13B Antibody

description :

The Mouse BAFF/BLyS/TNFSF13B Antibody from R&D Systems is a rat monoclonal antibody to BAFF/BLyS/TNFSF13B. This antibody reacts with human,mouse. The Mouse BAFF/BLyS/TNFSF13B Antibody has been validated for the following applications: Intracellular Staining by Flow Cytometry,CyTOF-ready,ELISA Development,ELISA Development (Capture),Flow Cytometry,Western Blot.

target :

BAFF/BLyS/TNFSF13B

unit size :

100 ug (also 25 ug, 500 ug)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

121808

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse BAFF, Ala127-Leu309, Accession # Q9WU72

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects mouse BAFF in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse (rm) 4-1BB Ligand, rmEDA, rmFas Ligand, rmOX40 Ligand, rmTNF-alpha , rmTRANCE, rmTWEAK, recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhGITR Ligand, rhLIGHT, rhLymphotoxin alpha 1¡ß2, rhLymphotoxin alpha 2¡ß1, rhTNF-alpha , rhTRAIL, rhVEGI, recombinant canine, cotton rat, equine, feline, porcine, or rat TNF-alpha .

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

gene symbol :

TNFSF13B

accessionNumbers :

Q9WU72

applications :

Intracellular Staining by Flow Cytometry,CyTOF-ready,ELISA Development,ELISA Development (Capture),Flow Cytometry,Western Blot

product keywords :

MAB1357, mBAFF/BLyS MAb Cl 121808, Rat Anti-Mouse BAFF/BLyS/TNFSF13B Monoclonal Antibody, Anti-BAFF, Anti-BLyS, Anti-TNFSF13B, Rat Anti Mouse BAFF/BLyS/TNFSF13B Monoclonal Antibody, Anti-mBAFF, cytokinegrowthfact, TNFSF 13B, cytokine, cytokines, sCD257, sBAFF, TNFSFCoReg

USD :

459

USD 2025 :

469 USD

alt names :

ApoL related ligand TALL-1, B lymphocyte stimulator, BAFFB-cell activating factor, B-cell-activating factor, BLyS, BLYSB-lymphocyte stimulator, CD257, CD257 antigen, Dendritic cell-derived TNF-like molecule, DTL, TALL1, TALL-1delta BAFF, TALL1Delta4 BAFF, THANK, TNF and ApoL-related leukocyte expressed ligand 1, TNF- and APOL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNFSF13B, TNFSF20, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor superfamily, member 13b, tumor necrosis factor-like protein ZTNF4, ZTNF4

more info or order :

R&D Systems product webpage