product summary
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company name :
R&D Systems
product type :
antibody
product name :
p53 Antibody
catalog :
MAB1355
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
184721
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 8
Reference
Meah A, Vedarethinam V, Bronstein R, Gujarati N, Jain T, Mallipattu S, et al. Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers. Biosensors (Basel). 2023;13: pubmed publisher
x15a witalska M, Filip Psurska B, Milczarek M, Psurski M, Moszy x144 ska A, D x105 browska A, et al. Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis. J Cell Mol Med. 2022;26:3950-3964 pubmed publisher
Liśkiewicz D, Liskiewicz A, Grabowski M, Nowacka Chmielewska M, Jabłońska K, Wojakowska A, et al. Upregulation of hepatic autophagy under nutritional ketosis. J Nutr Biochem. 2021;93:108620 pubmed publisher
Wang J, Dubiel D, Wu Y, Cheng Y, Wolf D, Dubiel W. CSN7B defines a variant COP9 signalosome complex with distinct function in DNA damage response. Cell Rep. 2021;34:108662 pubmed publisher
Song X, Narzt M, Nagelreiter I, Hohensinner P, Terlecki Zaniewicz L, Tschachler E, et al. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo. Redox Biol. 2017;11:219-230 pubmed publisher
Levy G, Bomze D, Heinz S, Ramachandran S, Noerenberg A, Cohen M, et al. Long-term culture and expansion of primary human hepatocytes. Nat Biotechnol. 2015;33:1264-1271 pubmed publisher
Olsson M, Vakifahmetoglu H, Abruzzo P, Högstrand K, Grandien A, Zhivotovsky B. DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis. Oncogene. 2009;28:1949-59 pubmed publisher
Vakifahmetoglu H, Olsson M, Orrenius S, Zhivotovsky B. Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage. Oncogene. 2006;25:5683-92 pubmed
image
image 1 :
R&D Systems MAB1355 image 1
Detection of Human p53 antibody by Western Blot.
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB1355
SKU :
MAB1355
product name :
p53 Antibody
Description :
The Human/Mouse/Rat p53 Antibody from R&D Systems is a mouse monoclonal antibody to p53. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat p53 Antibody has been validated for the following applications: Western Blot, Immunoprecipitation, Immunocytochemistry.
target :
p53
category :
Primary Antibodies
unit size :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
184721
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human p53, Asp7-Asp393, Accession # P04637
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human, Mouse, Rat
specificity :
Detects human, mouse, and rat p53.
gene symbol :
TP53
accessionNumbers :
P04637
applications :
Western Blot, Immunoprecipitation, Immunocytochemistry
USD :
479 USD
alt names :
Antigen NY-CO-13, BCC7, FLJ92943, LFS1, LFS1TRP53, p53, p53 tumor suppressor, P53cellular tumor antigen p53, Phosphoprotein p53, TP53, transformation-related protein 53, TRP53, tumor protein p53, Tumor suppressor p53
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.