Human Integrin alpha 4/CD49d Antibody | R&D Systems MAB1354-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Integrin alpha 4/CD49d Antibody

catalog :

MAB1354-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7.2R

reactivity :

human

application :

immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Su Y, Luo Z, Sun D, Yang B, Li Q. The Force-Dependent Mechanism of an Integrin α4β7-MAdCAM-1 Interaction. Int J Mol Sci. 2023;24: pubmed publisher
Howden J, Michael M, Hight Warburton W, Parsons M. α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions. BMC Biol. 2021;19:130 pubmed publisher
Karpova D, Rettig M, Ritchey J, Cancilla D, Christ S, Gehrs L, et al. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. J Clin Invest. 2019;129:2745-2759 pubmed publisher
Zhang P, Fu C, Hu Y, Dong C, Song Y, Song E. C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCÎ¶ tumor-suppressive activities and regulating integrin affinity modulation. Sci Rep. 2015;5:9275 pubmed publisher
Silverman M, Haas C, Rad A, Arbab A, Koch A. The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium. Arthritis Rheum. 2007;56:1817-26 pubmed
van Grevenstein W, Hofland L, van Rossen M, van Koetsveld P, Jeekel J, van Eijck C. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig Dis Sci. 2007;52:2775-83 pubmed
Carman C, Springer T. A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them. J Cell Biol. 2004;167:377-88 pubmed

product information

master code :

MAB1354

SKU :

MAB1354-100

product name :

Human Integrin alpha 4/CD49d Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Integrin alpha 4/CD49d Antibody from R&D Systems is a mouse monoclonal antibody to Integrin alpha 4/CD49d. This antibody reacts with human. The Human Integrin alpha 4/CD49d Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Neutralization,Immunocytochemistry,CyTOF-ready.

target :

Integrin alpha 4/CD49d

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

7.2R

conjugate :

Unconjugated

host :

Mouse

immunogen :

DX-3 human melanoma cell line

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Integrin alpha 4/CD49d. Recognizes the human Integrin alpha 4/CD49d subunit.

gene symbol :

ITGA4

top caption :

Detection of Integrin a4/CD49d antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

applications :

Bioassay,Flow Cytometry,Neutralization,Immunocytochemistry,CyTOF-ready

USD :

459 USD

alt names :

269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), ITGA4, MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4, VLA-4 subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage