Integrin alpha 6/CD49f Antibody | R&D Systems MAB13501 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Integrin alpha 6/CD49f Antibody

catalog :

MAB13501

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GoH3

reactivity :

human, mouse, bovine

application :

immunohistochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 16

Reference
Bae E, Huang P, M xfc ller Greven G, Hambardzumyan D, Sloan A, Nowacki A, et al. Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis. Nat Commun. 2022;13:4268 pubmed publisher
Ouji Y, Misu M, Kitamura T, Okuzaki D, Yoshikawa M. Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture. Sci Rep. 2022;12:11011 pubmed publisher
Shook B, Wasko R, Mano O, Rutenberg Schoenberg M, Rudolph M, Zirak B, et al. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020;26:880-895.e6 pubmed publisher
Jia Y, You X, Ma N, Li H, Liu G, Wang Y, et al. Phenotypic Analysis of BrdU Label-Retaining Cells during the Maturation of Conducting Airway Epithelium in a Porcine Lung. Stem Cells Int. 2019;2019:7043890 pubmed publisher
Weng N, Cheung C, Talbot P. Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling. Stem Cell Res. 2018;33:233-246 pubmed publisher
Yoldi G, Pellegrini P, Trinidad E, Cordero A, Gomez Miragaya J, Serra Musach J, et al. RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell Differentiation. Cancer Res. 2016;76:5857-5869 pubmed
Unruh D, Unlü B, Lewis C, Qi X, Chu Z, Sturm R, et al. Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:25264-75 pubmed publisher
Seano G, Chiaverina G, Gagliardi P, di Blasio L, Puliafito A, Bouvard C, et al. Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis. Nat Cell Biol. 2014;16:931-41, 1-8 pubmed publisher
Samarelli A, Riccitelli E, Bizzozero L, Silveira T, Seano G, Pergolizzi M, et al. Neuroligin 1 induces blood vessel maturation by cooperating with the ?6 integrin. J Biol Chem. 2014;289:19466-76 pubmed publisher
Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M. Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins. Matrix Biol. 2014;36:5-14 pubmed publisher
Smadja D, Guerin C, Boscolo E, Bieche I, Mulliken J, Bischoff J. ?6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cells. Stem Cells. 2014;32:684-93 pubmed publisher
Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams R, et al. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J. 2013;32:629-44 pubmed publisher
Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, et al. CD98hc (SLC3A2) regulation of skin homeostasis wanes with age. J Exp Med. 2013;210:173-90 pubmed publisher
Oki Y, Ono H, Motohashi T, Sugiura N, Nobusue H, Kano K. Dedifferentiated follicular granulosa cells derived from pig ovary can transdifferentiate into osteoblasts. Biochem J. 2012;447:239-48 pubmed
Liu D, Lobie P. Transcriptional activation of p53 by Pitx1. Cell Death Differ. 2007;14:1893-907 pubmed
Eto D, Jones T, Sundsbak J, Mulvey M. Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. PLoS Pathog. 2007;3:e100 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB13501

SKU :

MAB13501

product name :

Integrin alpha 6/CD49f Antibody

Description :

The Human/Mouse/Bovine Integrin alpha 6/CD49f Antibody from R&D Systems is a rat monoclonal antibody to Integrin alpha 6/CD49f. This antibody reacts with human, mouse, bovine. The Human/Mouse/Bovine Integrin alpha 6/CD49f Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-reported.

target :

Integrin alpha 6/CD49f

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

GoH3

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse mammary tumor cells

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse, Bovine

specificity :

Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit.

gene symbol :

ITGA6

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-reported

extended description :

Clone GoH3 was used by HLDA to establish CD designation

USD :

479 USD

product details :

Clone GoH3 was used by HLDA to establish CD designation

alt names :

CD49 antigen-like family member F, CD49f, CD49f antigen, DKFZp686J01244, FLJ18737, integrin alpha-6, integrin alpha6B, integrin, alpha 6, ITGA6, ITGA6B, Platelet gpl, VLA-6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage