Human/Mouse Proinsulin Antibody | R&D Systems MAB13361 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Proinsulin Antibody

catalog :

MAB13361

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

253627

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig s3h	Borg D, Faridi P, Giam K, Reeves P, Fotheringham A, McCarthy D, et al. Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model. Metabolites. 2021;11: pubmed publisher
	Wu Y, Wong C, Chiles E, Mellinger A, Bae H, Jung S, et al. Glycerate from intestinal fructose metabolism induces islet cell damage and glucose intolerance. Cell Metab. 2022;34:1042-1053.e6 pubmed publisher
	Zhang X, Wang X, Yuan Z, Radford S, Liu C, Libutti S, et al. Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis. Cell Rep. 2021;34:108830 pubmed publisher
	Lee J, Kim K, Cho J, Bae J, O Leary T, Johnson J, et al. Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production. JCI Insight. 2020;5: pubmed publisher
	Sambataro M, Sambado L, Trevisiol E, Cacciatore M, Furlan A, Stefani P, et al. Proinsulin-expressing dendritic cells in type 2 neuropathic diabetic patients with and without foot lesions. FASEB J. 2018;32:3742-3751 pubmed publisher
	Borg D, Yap F, Keshvari S, Simmons D, Gallo L, Fotheringham A, et al. Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets. 2017;: pubmed publisher
	Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
	Jonatan D, Spence J, Method A, Kofron M, Sinagoga K, Haataja L, et al. Sox17 regulates insulin secretion in the normal and pathologic mouse β cell. PLoS ONE. 2014;9:e104675 pubmed publisher
	Cao M, Mao Z, Kam C, Xiao N, Cao X, Shen C, et al. PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance. PLoS Biol. 2013;11:e1001541 pubmed publisher
	Chen W, Begum S, Opare Addo L, Garyu J, Gibson T, Bothwell A, et al. Promotion of beta-cell differentiation in pancreatic precursor cells by adult islet cells. Endocrinology. 2009;150:570-9 pubmed publisher

product information

master code :

MAB13361

SKU :

MAB13361

product name :

Human/Mouse Proinsulin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse Proinsulin Antibody from R&D Systems is a mouse monoclonal antibody to Proinsulin. This antibody reacts with human,mouse. The Human/Mouse Proinsulin Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

Proinsulin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

253627

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Proinsulin, Phe25-Asn110, Accession # P01308

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse Proinsulin. Does not detect mature insulin.

gene symbol :

INS

top caption :

Proinsulin antibody in beta TC-6 Mouse Cell Line by Immunocytochemistry (ICC).

accessionNumbers :

P01308

applications :

Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

489 USD

alt names :

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage