Human TREM-1 Antibody | R&D Systems MAB1278 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TREM-1 Antibody

catalog :

MAB1278

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

193015

reactivity :

human

application :

flow cytometry, blocking or activating experiments

citations: 13

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 5a	Zhang G, Liu H, Huang J, Chen S, Pan X, Huang H, et al. TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer. Oncotarget. 2016;7:40508-40517 pubmed publisher
	Campbell G, To R, Spector S. TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function. MBio. 2019;10: pubmed publisher
	Canavan M, Walsh A, Bhargava V, Wade S, McGarry T, Marzaioli V, et al. Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis. JCI Insight. 2018;3: pubmed publisher
	Jolly L, Carrasco K, Derive M, Lemarié J, Boufenzer A, Gibot S. Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock. Cardiovasc Res. 2018;114:907-918 pubmed publisher
	Aldasoro Arguinano A, Dadé S, Stathopoulou M, Derive M, Coumba Ndiaye N, Xie T, et al. TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin. PLoS ONE. 2017;12:e0182226 pubmed publisher
	Tammaro A, Derive M, Gibot S, Leemans J, Florquin S, Dessing M. TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives. Pharmacol Ther. 2017;177:81-95 pubmed publisher
	Read C, Kuijper J, Hjorth S, Heipel M, Tang X, Fleetwood A, et al. Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1. J Immunol. 2015;194:1417-21 pubmed publisher
	Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
	Ingersoll M, Spanbroek R, Lottaz C, Gautier E, Frankenberger M, Hoffmann R, et al. Comparison of gene expression profiles between human and mouse monocyte subsets. Blood. 2010;115:e10-9 pubmed publisher
	Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H. Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis. Arthritis Rheum. 2009;60:1615-23 pubmed publisher
	Ho C, Liao W, Wang C, Lu Y, Huang H, Chen H, et al. TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer. Am J Respir Crit Care Med. 2008;177:763-70 pubmed
	Horonenko G, Hoyt J, Robbins R, Singarajah C, Umar A, Pattengill J, et al. Soluble triggering receptor expressed on myeloid cell-1 is increased in patients with ventilator-associated pneumonia: a preliminary report. Chest. 2007;132:58-63 pubmed
	Fortin C, Lesur O, Fulop T. Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4. Int Immunol. 2007;19:41-50 pubmed

product information

brand :

R&D Systems

master code :

MAB1278

SKU :

MAB1278-100

product name :

Human TREM-1 Antibody

description :

The Human TREM-1 Antibody from R&D Systems is a mouse monoclonal antibody to TREM1. This antibody reacts with human. The Human TREM-1 Antibody has been validated for the following applications: Flow Cytometry, Agonist Activity, CyTOF-ready.

target :

TREM1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

193015

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TREM-1, Ala21-Asn205, Accession # Q9NP99

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human TREM-1 in direct ELISAs.

gene symbol :

TREM1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB1278

accessionNumbers :

Q9NP99

applications :

Flow Cytometry, Agonist Activity, CyTOF-ready

extended description :

Clone 193015 was used by HLDA to establish CD designation

2020 USD :

339

2021 USD :

369 USD

product details :

Clone 193015 was used by HLDA to establish CD designation

alt names :

CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.