product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human Jagged 1 Antibody
catalog :
MAB12771-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
188323
reactivity :
human
application :
neutralization
more info or order :
citations: 3
Reference
Choi J, Rim J, Jang S, Park J, Park H, Cho J, et al. The role of Jagged1 as a dynamic switch of cancer cell plasticity in PDAC assembloids. Theranostics. 2022;12:4431-4445 pubmed publisher
Robinson N, Miyagi M, Scarborough J, Scott J, Taylor D, Schiemann W. SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling. Sci Signal. 2021;14: pubmed publisher
Jung Y, Wang J, Song J, Shiozawa Y, Wang J, Havens A, et al. Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood. 2007;110:82-90 pubmed
product information
master code :
MAB12771
SKU :
MAB12771-100
product name :
Human Jagged 1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human Jagged 1 Antibody from R&D Systems is a mouse monoclonal antibody to Jagged 1. This antibody reacts with human. The Human Jagged 1 Antibody has been validated for the following applications: Neutralization,Binding Assay.
target :
Jagged 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
188323
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
NS0-derived recombinant human Jagged 1, Ser32-Asp296, Accession # P78504
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Jagged 1 in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant human Jagged 2 and recombinant rat Jagged 1 is observed.
gene symbol :
JAG1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Alkaline Phosphatase Production Induced by Jagged 1 and Neutralization by Human Jagged 1 Antibody.
accessionNumbers :
P78504
applications :
Binding Assay,Neutralization
USD :
479 USD
alt names :
AGS, AHDMGC104644, Alagille syndrome, AWS, CD339, CD339 antigen, HJ1, JAG1, jagged 1, Jagged1, JAGL1, protein jagged-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.