Human PDGF R alpha Antibody | R&D Systems MAB1264 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human PDGF R alpha Antibody

catalog :

MAB1264

quantity :

250 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PRa292

reactivity :

human, mouse

application :

immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 10

Reference
de Villenfagne L, Sablon A, Demoulin J. PDGFRA K385 mutants in myxoid glioneuronal tumors promote receptor dimerization and oncogenic signaling. Sci Rep. 2024;14:7204 pubmed publisher
Khan T, Seddon A, Dalgleish A, Khelwatty S, Ioannou N, Mudan S, et al. Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancr. Oncol Rep. 2020;44:2581-2594 pubmed publisher
Stringer B, Day B, D Souza R, Jamieson P, Ensbey K, Bruce Z, et al. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep. 2019;9:4902 pubmed publisher
Mathias L, Khong S, Spyroglou L, Payne N, Siatskas C, Thorburn A, et al. Alveolar macrophages are critical for the inhibition of allergic asthma by mesenchymal stromal cells. J Immunol. 2013;191:5914-24 pubmed publisher
Velghe A, van Cauwenberghe S, Polyansky A, Chand D, Montano Almendras C, Charni S, et al. PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations. Oncogene. 2014;33:2568-76 pubmed publisher
Walczak P, All A, Rumpal N, Gorelik M, Kim H, Maybhate A, et al. Human glial-restricted progenitors survive, proliferate, and preserve electrophysiological function in rats with focal inflammatory spinal cord demyelination. Glia. 2011;59:499-510 pubmed publisher
Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, Holy X, et al. Mesenchymal stem cell abnormalities in patients with multiple myeloma. Leuk Lymphoma. 2007;48:2032-41 pubmed
Zhang M, Veselits M, O Neill S, Hou P, Reddi A, Berlin I, et al. Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor. J Immunol. 2007;179:4435-43 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed

product information

master code :

MAB1264

SKU :

MAB1264

product name :

Human PDGF R alpha Antibody

unit size :

250 ug (also 25 ug)

description :

The Human PDGF R alpha Antibody from R&D Systems is a mouse monoclonal antibody to PDGFR alpha. This antibody reacts with human,mouse. The Human PDGF R alpha Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Immunocytochemistry.

target :

PDGF R alpha

category :

Primary Antibodies

buffer :

Supplied as a 0.2 ╡m filtered solution in PBS. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

PRa292

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human osteosarcoma cell membrane extracts

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human PDGF R alpha . Recognizes the PDGF receptor alpha -subunit; it does not recognize the PDGF receptor ▀-subunit. Binds to the PDGF receptor alpha -subunit of primate species (human, monkey, baboon) and dog. Does not recognize rat or mouse receptors and its ability to bind to receptors from other species has not been tested.

gene symbol :

PDGFRA

applications :

Flow Cytometry,Immunoprecipitation,Immunocytochemistry

USD :

439 USD

alt names :

alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, EC 2.7.10, EC 2.7.10.1, MGC74795, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PDGF-R-alpha, platelet-derived growth factor receptor, alpha polypeptide, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein, RHEPDGFRA

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C, as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 6 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage