Human Fas Ligand/TNFSF6 Antibody | R&D Systems MAB126 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Fas Ligand/TNFSF6 Antibody

catalog :

MAB126

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100419

reactivity :

human

application :

neutralization, flow cytometry, blocking or activating experiments

citations: 13

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig s2	Tanzer M, Khan N, Rickard J, Etemadi N, Lalaoui N, Spall S, et al. Combination of IAP antagonist and IFNÎ³ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ. 2017;24:481-491 pubmed publisher
blocking or activating experiments; human; loading ...; fig s2a	Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed publisher
	Liu B, Zhang Y, Fan Y, Wang S, Li Z, Deng M, et al. Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL. Cancer Sci. 2019;110:2145-2155 pubmed publisher
	Idelson M, Alper R, Obolensky A, Yachimovich Cohen N, Rachmilewitz J, Ejzenberg A, et al. Immunological Properties of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. Stem Cell Reports. 2018;11:681-695 pubmed publisher
	Kim M, Pyo S, Kang C, Lee C, Lee H, Choi S, et al. Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer. PLoS ONE. 2018;13:e0198347 pubmed publisher
	Nakachi S, Sumitomo S, Tsuchida Y, Tsuchiya H, Kono M, Kato R, et al. Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis. Arthritis Res Ther. 2017;19:97 pubmed publisher
	Köstlin N, Vogelmann M, Spring B, Schwarz J, Feucht J, Hartel C, et al. Granulocytic myeloid-derived suppressor cells from human cord blood modulate T-helper cell response towards an anti-inflammatory phenotype. Immunology. 2017;152:89-101 pubmed publisher
	Zheng J, Wu W, Liu Y, Xiang Z, Liu M, Chan K, et al. The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice. PLoS ONE. 2015;10:e0135999 pubmed publisher
	Yang K, Wang Y, Chang C, Huang S, Huang Y, Chi M, et al. Reciprocal complementation of the tumoricidal effects of radiation and natural killer cells. PLoS ONE. 2013;8:e61797 pubmed publisher
	Inoue T, Tashiro Y, Takeuchi M, Otani T, Tsuji Takayama K, Okochi A, et al. Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins. Int J Oncol. 2011;38:1299-306 pubmed publisher
	Navenot J, Fujii N, Peiper S. KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. Mol Pharmacol. 2009;75:1074-83 pubmed publisher
	Krysov S, Rowley T, Al Shamkhani A. Inhibition of p38 mitogen-activated protein kinase unmasks a CD30-triggered apoptotic pathway in anaplastic large cell lymphoma cells. Mol Cancer Ther. 2007;6:703-11 pubmed
	Georgopoulos N, Steele L, Thomson M, Selby P, Southgate J, Trejdosiewicz L. A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. Cell Death Differ. 2006;13:1789-801 pubmed

product information

brand :

R&D Systems

master code :

MAB126

SKU :

MAB126-100

product name :

Human Fas Ligand/TNFSF6 Antibody

description :

The Human Fas Ligand/TNFSF6 Antibody from R&D Systems is a mouse monoclonal antibody to Fas Ligand/TNFSF6. This antibody reacts with human. The Human Fas Ligand/TNFSF6 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

Fas Ligand/TNFSF6

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

100419

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Fas Ligand/TNFSF6, Pro134-Leu281, Accession # P48023

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Fas Ligand/TNFSF6 in ELISAs.

gene symbol :

FASLG

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB126

accessionNumbers :

P48023

applications :

Flow Cytometry, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.