Fas Ligand/TNFSF6 Antibody | R&D Systems MAB126-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Fas Ligand/TNFSF6 Antibody

catalog :

MAB126-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

453 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100419

reactivity :

human

application :

ELISA, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 15

Reference
Shankar S, Stolp J, Juvet S, Beckett J, Macklin P, Issa F, et al. Ex vivo-expanded human CD19+TIM-1+ regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis. Nat Commun. 2022;13:3121 pubmed publisher
Kajikawa O, Herrero R, Chow Y, Hung C, Matute Bello G. The bioactivity of soluble Fas ligand is modulated by key amino acids of its stalk region. PLoS ONE. 2021;16:e0253260 pubmed publisher
Liu B, Zhang Y, Fan Y, Wang S, Li Z, Deng M, et al. Leucine-rich repeat neuronal protein-1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL. Cancer Sci. 2019;110:2145-2155 pubmed publisher
Idelson M, Alper R, Obolensky A, Yachimovich Cohen N, Rachmilewitz J, Ejzenberg A, et al. Immunological Properties of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. Stem Cell Reports. 2018;11:681-695 pubmed publisher
Kim M, Pyo S, Kang C, Lee C, Lee H, Choi S, et al. Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer. PLoS ONE. 2018;13:e0198347 pubmed publisher
Nakachi S, Sumitomo S, Tsuchida Y, Tsuchiya H, Kono M, Kato R, et al. Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis. Arthritis Res Ther. 2017;19:97 pubmed publisher
Köstlin N, Vogelmann M, Spring B, Schwarz J, Feucht J, Hartel C, et al. Granulocytic myeloid-derived suppressor cells from human cord blood modulate T-helper cell response towards an anti-inflammatory phenotype. Immunology. 2017;152:89-101 pubmed publisher
Tanzer M, Khan N, Rickard J, Etemadi N, Lalaoui N, Spall S, et al. Combination of IAP antagonist and IFNÎ³ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ. 2017;24:481-491 pubmed publisher
Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed publisher
Zheng J, Wu W, Liu Y, Xiang Z, Liu M, Chan K, et al. The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice. PLoS ONE. 2015;10:e0135999 pubmed publisher
Yang K, Wang Y, Chang C, Huang S, Huang Y, Chi M, et al. Reciprocal complementation of the tumoricidal effects of radiation and natural killer cells. PLoS ONE. 2013;8:e61797 pubmed publisher
Inoue T, Tashiro Y, Takeuchi M, Otani T, Tsuji Takayama K, Okochi A, et al. Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins. Int J Oncol. 2011;38:1299-306 pubmed publisher
Navenot J, Fujii N, Peiper S. KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. Mol Pharmacol. 2009;75:1074-83 pubmed publisher
Krysov S, Rowley T, Al Shamkhani A. Inhibition of p38 mitogen-activated protein kinase unmasks a CD30-triggered apoptotic pathway in anaplastic large cell lymphoma cells. Mol Cancer Ther. 2007;6:703-11 pubmed
Georgopoulos N, Steele L, Thomson M, Selby P, Southgate J, Trejdosiewicz L. A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. Cell Death Differ. 2006;13:1789-801 pubmed

image

image 1 :

Detection of Fas Ligand/TNFSF6 antibody in HEK293 Human Cell Line Transfected with Human Fas Ligand/TNFSF6 and eGFP antibody by Flow Cytometry.

product information

brand :

R&D Systems

master code :

MAB126

SKU :

MAB126-100

product name :

Fas Ligand/TNFSF6 Antibody

description :

The Human Fas Ligand/TNFSF6 Antibody from R&D Systems is a mouse monoclonal antibody to Fas Ligand/TNFSF6. This antibody reacts with human. The Human Fas Ligand/TNFSF6 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

Fas Ligand/TNFSF6

category :

Primary Antibodies

sizes available :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

100419

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Fas Ligand/TNFSF6, Pro134-Leu281, Accession # P48023

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Fas Ligand/TNFSF6 in ELISAs

gene symbol :

FASLG

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P48023

applications :

Flow Cytometry, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

453 USD

alt names :

apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage