Human Fc gamma RI/CD64 Antibody | R&D Systems MAB1257-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Fc gamma RI/CD64 Antibody

catalog :

MAB1257-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10.1

reactivity :

human

application :

immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Reference
K xfc nzel C, Abdolzade Bavil A, Engel A, Pleitner M, Schick E, Stubenrauch K. Assay concept for detecting anti-drug IgM in human serum samples by using a novel recombinant human IgM positive control. Bioanalysis. 2021;13:253-263 pubmed publisher
Chang M, Cheng H, Hsu K, Hsu Y, Kao C, Chang Y, et al. NKG2A Down-Regulation by Dasatinib Enhances Natural Killer Cytotoxicity and Accelerates Effective Treatment Responses in Patients With Chronic Myeloid Leukemia. Front Immunol. 2018;9:3152 pubmed publisher
Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed publisher
Hassan U, Ghonge T, Reddy B, Patel M, Rappleye M, Taneja I, et al. A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification. Nat Commun. 2017;8:15949 pubmed publisher
McWilliams E, Mele J, Cheney C, Timmerman E, Fiazuddin F, Strattan E, et al. Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia. Oncoimmunology. 2016;5:e1226720 pubmed
He X, Sun X, Wang J, Wang X, Zhang Q, Tzipori S, et al. Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A. Infect Immun. 2009;77:2294-303 pubmed publisher
Schleinitz N, Cognet C, Guia S, Laugier Anfossi F, Baratin M, Pouget J, et al. Expression of the CD85j (leukocyte Ig-like receptor 1, Ig-like transcript 2) receptor for class I major histocompatibility complex molecules in idiopathic inflammatory myopathies. Arthritis Rheum. 2008;58:3216-23 pubmed publisher
Yamaguchi Y, Seta N, Kaburaki J, Kobayashi K, Matsuura E, Kuwana M. Excessive exposure to anionic surfaces maintains autoantibody response to beta(2)-glycoprotein I in patients with antiphospholipid syndrome. Blood. 2007;110:4312-8 pubmed

product information

master code :

MAB1257

SKU :

MAB1257-100

product name :

Human Fc gamma RI/CD64 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Fc gamma RI/CD64 Antibody from R&D Systems is a mouse monoclonal antibody to Fc gamma RI/CD64. This antibody reacts with human. The Human Fc gamma RI/CD64 Antibody has been validated for the following applications: Bioassay,Neutralization,Immunohistochemistry-Frozen,Flow Cytometry,Immunocytochemistry,CyTOF-ready.

target :

Fc gamma RI/CD64

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

10.1

conjugate :

Unconjugated

host :

Mouse

immunogen :

Rheumatoid synovial fluid cells and fibronectin purified monocytes

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Fc gamma RI/CD64.

gene symbol :

FCGR1A

top caption :

Detection of Fc? RI/CD64 antibody in Human Blood Monocytes antibody by Flow Cytometry.

applications :

Bioassay,Neutralization,Immunohistochemistry-Frozen,Flow Cytometry,Immunocytochemistry,CyTOF-ready

extended description :

Clone 10.1 was used by HLDA to establish CD designation

USD :

479 USD

product details :

Clone 10.1 was used by HLDA to establish CD designation

alt names :

CD64, CD64 antigen, CD64a, CD64b, Fc fragment of IgG, high affinity Ia, receptor (CD64), FCG1, Fc-gamma receptor I B2, Fc-gamma RI, Fc-gamma RIA, FcgammaRIa, FCGR1, FCGR1B, FcgRI, FcgRIA, FCRI, FcRIA, FLJ18345, high affinity Ia, receptor for (CD64), high affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage