product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Semaphorin 3A Antibody
catalog :
MAB1250
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
215803
reactivity :
human, mouse, rat
application :
western blot, neutralization, flow cytometry
more info or order :
citations: 7
Reference
Lewis P, Silajd x17e i x107 E, Smith H, Bates N, Smith C, Mancini F, et al. A secreted proteomic footprint for stem cell pluripotency. PLoS ONE. 2024;19:e0299365 pubmed publisher
Sen S, Lux C, Erber R. A Potential Role of Semaphorin 3A during Orthodontic Tooth Movement. Int J Mol Sci. 2021;22: pubmed publisher
Leclerc M, Voilin E, Gros G, Corgnac S, de Montpreville V, Validire P, et al. Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1. Nat Commun. 2019;10:3345 pubmed publisher
Podojil J, Chiang M, Ifergan I, Copeland R, Liu L, Maloveste S, et al. B7-H4 Modulates Regulatory CD4+ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex. J Immunol. 2018;201:897-907 pubmed publisher
Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, et al. Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A. PLoS Biol. 2014;12:e1001808 pubmed publisher
Chakraborty G, Kumar S, Mishra R, Patil T, Kundu G. Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model. PLoS ONE. 2012;7:e33633 pubmed publisher
Tran Van H, Avota E, Börtlein C, Mueller N, Schneider Schaulies S. Measles virus modulates dendritic cell/T-cell communication at the level of plexinA1/neuropilin-1 recruitment and activity. Eur J Immunol. 2011;41:151-63 pubmed publisher
product information
master code :
MAB1250
SKU :
MAB1250
product name :
Human Semaphorin 3A Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Semaphorin 3A Antibody from R&D Systems is a mouse monoclonal antibody to Semaphorin 3A. This antibody reacts with human,mouse,rat. The Human Semaphorin 3A Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Neutralization,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
Semaphorin 3A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
215803
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Semaphorin 3A, Lys26-Val771 (Arg555Ala, Arg552Ala), Accession # Q14563
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human Semaphorin 3A in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Semaphorin 3B, 3E, 6A, 6B, 6C, 6D, 7A, recombinant mouse Semaphorin 3C, or 3F is observed.
gene symbol :
SEMA3A
accessionNumbers :
Q14563
applications :
Western Blot,Flow Cytometry,Neutralization,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
479 USD
alt names :
(semaphorin) 3A, coll-1, collapsin 1, Hsema-I, Hsema-III, MGC133243, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, Sema III, SEMA1, Sema3A, SEMAD, SEMAIII, SEMAL, semaphorin D, Semaphorin III, semaphorin L, semaphorin-3A, SemD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.