BAFF/BLyS/TNFSF13B Antibody | R&D Systems MAB124-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

BAFF/BLyS/TNFSF13B Antibody

catalog :

MAB124-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

148725

reactivity :

human

application :

neutralization

more info or order :

R&D Systems product webpage

citations: 5

Reference
Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, et al. Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis. J Neuroinflammation. 2018;15:114 pubmed publisher
Chang L, Li Y, Kaplan D. Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis. Sci Rep. 2016;6:36862 pubmed publisher
Giacomini E, Severa M, Rizzo F, Mechelli R, Annibali V, Ristori G, et al. IFN-? therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients. Eur J Immunol. 2013;43:1963-72 pubmed publisher
Benito Miguel M, García Carmona Y, Balsa A, Bautista Caro M, Arroyo Villa I, Cobo Ibáñez T, et al. IL-15 expression on RA synovial fibroblasts promotes B cell survival. PLoS ONE. 2012;7:e40620 pubmed publisher
Fu L, Lin Lee Y, Pham L, Tamayo A, Yoshimura L, Ford R. Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas. Blood. 2006;107:4540-8 pubmed

image

image 1 :

Cell Proliferation Induced by BAFF/BLyS/TNFSF13B and Neutralization by Human BAFF/BLyS/TNFSF13B Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB124

SKU :

MAB124-100

product name :

BAFF/BLyS/TNFSF13B Antibody

Description :

The Human BAFF/BLyS/TNFSF13B Antibody from R&D Systems is a mouse monoclonal antibody to BAFF/BLyS/TNFSF13B. This antibody reacts with human. The Human BAFF/BLyS/TNFSF13B Antibody has been validated for the following applications: Neutralization.

target :

BAFF/BLyS/TNFSF13B

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

148725

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BAFF, Ala134-Leu285, Accession # Q9Y275

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human BAFF in direct ELISAs.

gene symbol :

TNFSF13B

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

Q9Y275

applications :

Neutralization

USD :

459 USD

alt names :

ApoL related ligand TALL-1, B lymphocyte stimulator, BAFFB-cell activating factor, B-cell-activating factor, BLyS, BLYSB-lymphocyte stimulator, CD257, CD257 antigen, Dendritic cell-derived TNF-like molecule, DTL, TALL1, TALL-1delta BAFF, TALL1Delta4 BAFF, THANK, TNF and ApoL-related leukocyte expressed ligand 1, TNF- and APOL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNFSF13B, TNFSF20, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor superfamily, member 13b, tumor necrosis factor-like protein ZTNF4, ZTNF4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage