product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse B220/CD45R Antibody
catalog :
MAB1217
quantity :
500 ug (also 25 ug)
price :
549 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RA3-6B2
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig 7f
Zheng J, MEYERHOLZ D, Wong L, Gelb M, Murakami M, Perlman S. Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. J Clin Invest. 2021;131: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Luo R, Cheng Y, Chang D, Liu T, Liu L, Pei G, et al. Tertiary lymphoid organs are associated with the progression of kidney damage and regulated by interleukin-17A. Theranostics. 2021;11:117-131 pubmed publisher
Anastasiadou D, Couturier N, Goel S, Argyris D, Vodopyanov S, Rivera Sanchez L, et al. Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer. bioRxiv. 2024;: pubmed publisher
Lagou M, Argyris D, Vodopyanov S, Gunther Cummins L, Hardas A, Poutahidis T, et al. Morphometric Analysis of the Thymic Epithelial Cell (TEC) Network Using Integrated and Orthogonal Digital Pathology Approaches. bioRxiv. 2024;: pubmed publisher
Cornuault L, H xe9 rion F, Bourguignon C, Rouault P, Foussard N, Alzieu P, et al. Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction. J Am Heart Assoc. 2023;12:e029279 pubmed publisher
Song J, Deshpande T, Zhang X, Hannocks M, Lycke N, Cardell S, et al. The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation. iScience. 2023;26:106753 pubmed publisher
Houde N, Beuret L, Bonaud A, Fortier Beaulieu S, Truchon Landry K, Aoidi R, et al. Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation. Cell Rep. 2022;38:110223 pubmed publisher
Härzschel A, Li L, Krenn P, Szenes Nagy E, Andrieux G, Bayer E, et al. Kindlin-3 maintains marginal zone B cells but confines follicular B cell activation and differentiation. J Leukoc Biol. 2022;111:745-758 pubmed publisher
Dorraji E, Oteiza A, Kuttner S, Martin Armas M, Kanapathippillai P, Garbarino S, et al. Positron emission tomography and single photon emission computed tomography imaging of tertiary lymphoid structures during the development of lupus nephritis. Int J Immunopathol Pharmacol. 2021;35:20587384211033683 pubmed publisher
Guimbal S, Cornuault L, Rouault P, Hollier P, Chapouly C, Bats M, et al. Mast Cells Are the Trigger of Small Vessel Disease and Diastolic Dysfunction in Diabetic Obese Mice. Arterioscler Thromb Vasc Biol. 2021;41:e193-e207 pubmed publisher
Dingler F, Wang M, Mu A, Millington C, Oberbeck N, Watcham S, et al. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell. 2020;80:996-1012.e9 pubmed publisher
Cassidy L, Young A, Young C, Soilleux E, Fielder E, Weigand B, et al. Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk. Nat Commun. 2020;11:307 pubmed publisher
Takeda K, WEBB T, Ning F, Shiraishi Y, Regan D, Chow L, et al. Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation. J Immunol. 2018;200:1261-1269 pubmed publisher
Rigo V, Emionite L, Daga A, Astigiano S, Corrias M, Quintarelli C, et al. Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma. Sci Rep. 2017;7:14049 pubmed publisher
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017;127:1574-1588 pubmed publisher
Yin Y, Zhao L, Zhang F, Zhang X. Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. Sci Rep. 2016;6:31874 pubmed publisher
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
Percopo C, Dyer K, Garcia Crespo K, Gabryszewski S, Shaffer A, Domachowske J, et al. B cells are not essential for Lactobacillus-mediated protection against lethal pneumovirus infection. J Immunol. 2014;192:5265-72 pubmed publisher
Kluger M, Ostmann A, Luig M, Meyer M, Goerke B, Paust H, et al. B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis. Eur J Immunol. 2014;44:683-93 pubmed publisher
Weitman E, Aschen S, Farias Eisner G, Albano N, Cuzzone D, Ghanta S, et al. Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes. PLoS ONE. 2013;8:e70703 pubmed publisher
De Palma A, Verbeken E, Van Aelst I, Van Den Steen P, Opdenakker G, Neyts J. Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis. Virology. 2008;382:20-7 pubmed publisher
Garner O, Yamaguchi Y, Esko J, Videm V. Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate. Immunology. 2008;125:420-9 pubmed publisher
product information
master code :
MAB1217
SKU :
MAB1217
product name :
Mouse B220/CD45R Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse B220/CD45R Antibody from R&D Systems is a rat monoclonal antibody to B220/CD45R. This antibody reacts with human,mouse,transgenic mouse. The Mouse B220/CD45R Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,Immunocytochemistry,CyTOF-reported.
target :
B220/CD45R
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
RA3-6B2
conjugate :
Unconjugated
host :
Rat
immunogen :
Abelson mouse leukemia virus-induced pre-B tumor cells
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse B220/CD45R.
gene symbol :
PTPRC
top caption :
B220/CD45R antibody in Mouse Splenocytes by Immunocytochemistry (ICC).
applications :
Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,Immunocytochemistry,CyTOF-reported
USD :
549 USD
alt names :
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.