product summary
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company name :
R&D Systems
product type :
antibody
product name :
Galectin-3 Antibody
catalog :
MAB1197
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
202213
reactivity :
human, mouse, rat
application :
western blot, ELISA, neutralization, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • mass cytometry; mouse; loading ...; fig s3
Lagnado A, Leslie J, Ruchaud Sparagano M, Victorelli S, Hirsova P, Ogrodnik M, et al. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner. EMBO J. 2021;40:e106048 pubmed publisher
Tao C, Cheng K, Ma Y, Hsu W, Chen Y, Fuh J, et al. Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2019;: pubmed publisher
Clemente T, Vieira N, Cerliani J, Adrain C, Lüthi A, Dominguez M, et al. Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery. Cell Death Dis. 2017;8:e3176 pubmed publisher
Chen Y, Ma Y, Lin C, Cheng S, Hsu W, Lee E. Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation. Front Mol Neurosci. 2017;10:217 pubmed publisher
Fermino M, Dias F, Lopes C, Souza M, Cruz A, Liu F, et al. Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection. Eur J Immunol. 2013;43:1806-17 pubmed publisher
Zhou L, Cao W, Xie C, Tian J, Zhou Z, Zhou Q, et al. The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis. Kidney Int. 2012;82:759-70 pubmed publisher
image
image 1 :
R&D Systems MAB1197 image 1
Detection of Mouse Galectin-3 antibody by Western Blot.
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
MAB1197
SKU :
MAB1197
product name :
Galectin-3 Antibody
description :
The Human/Mouse/Rat Galectin-3 Antibody from R&D Systems is a rat monoclonal antibody to Galectin-3. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Galectin-3 Antibody has been validated for the following applications: Simple Western,ELISA Capture (Matched Antibody Pair),Western Blot,Immunohistochemistry-Frozen,Neutralization.
target :
Galectin-3
unit size :
500 ug (also 25 ug)
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
202213
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse Galectin-3, Ala2-Ile264, Accession # P16110
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat Galectin-3 in Western blots. Detects human and mouse Galectin-3 in direct ELISAs. In direct ELISAs, no cross-reactivity with rhGalectin-2, -4, -8 or recombinant mouse Galectin-1, -4, or -7 is observed.
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
gene symbol :
LGALS3
accessionNumbers :
P16110
applications :
Simple Western,ELISA Capture (Matched Antibody Pair),Western Blot,Immunohistochemistry-Frozen,Neutralization
product keywords :
MAB1197, h/m/rGalectin-3 MAb Cl 202213, Rat Anti-Human/Mouse/Rat Galectin-3 Monoclonal Antibody, Anti-Galectin-3, Rat Anti Human/Mouse/Rat Galectin-3 Monoclonal Antibody, Anti-h/m/rGalectin-3, SC-20157, immunechecktargets, Galectin3, Galectin 3, eBP, epsilon BP, Lectin, LAG-3andLAG-3ligands
USD :
559
USD 2025 :
559 USD
alt names :
AGE-R3, Carbohydrate-binding protein 35, CBP 35,35 kDa lectin, CBP35, Gal-3, GAL3, galactin-3, Galactose-specific lectin 3, Galactoside-binding protein, GALBPCBP35, galectin-3, Galectin3, GALIG, IgE-binding protein, L29, L31, L-31, Laminin-binding protein, Lectin L-29, lectin, galactoside-binding, soluble, 3, LGALS2, LGALS3, Mac-2, Mac-2 antigen, MAC2GAL3
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.