TREM-1 Antibody | R&D Systems MAB1187-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

TREM-1 Antibody

catalog :

MAB1187-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

174031

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100; fig 1	Peritore A, D Amico R, Cordaro M, Siracusa R, Fusco R, Gugliandolo E, et al. PEA/Polydatin: Anti-Inflammatory and Antioxidant Approach to Counteract DNBS-Induced Colitis. Antioxidants (Basel). 2021;10: pubmed publisher
immunohistochemistry; human; 1:100; fig 1	Ramil Gómez O, Rodriguez Carmona A, Fernández Rodríguez J, Pérez Fontán M, Ferreiro Hermida T, López Pardo M, et al. Mitochondrial Dysfunction Plays a Relevant Role in Pathophysiology of Peritoneal Membrane Damage Induced by Peritoneal Dialysis. Antioxidants (Basel). 2021;10: pubmed publisher
immunohistochemistry; human; 1:100; fig 1	Blottner D, Capitanio D, Trautmann G, Furlan S, Gambara G, Moriggi M, et al. Nitrosative Redox Homeostasis and Antioxidant Response Defense in Disused Vastus lateralis Muscle in Long-Term Bedrest (Toulouse Cocktail Study). Antioxidants (Basel). 2021;10: pubmed publisher
immunohistochemistry; human; 1:100; fig 1	Yan T, Wu M, Lv S, Hu Q, Xu W, Zeng A, et al. Exosomes derived from microRNA-512-5p-transfected bone mesenchymal stem cells inhibit glioblastoma progression by targeting JAG1. Aging (Albany NY). 2021;13:9911-9926 pubmed publisher
immunohistochemistry; human; 1:100; fig 1	Azzimonti B, Raimondo L, Squarzanti D, Rosso T, Zanetta P, Aluffi Valletti P, et al. Macrophages expressing TREM-1 are involved in the progression of HPV16-related oropharyngeal squamous cell carcinoma. Ann Med. 2021;53:541-550 pubmed publisher
	Li Q, Zhao Y, Guo H, Li Q, Yan C, Li Y, et al. Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment. Autophagy. 2023;19:2639-2656 pubmed publisher
	Zhong W, Zhang J, Duan J, Zhang C, Ma S, Li Y, et al. TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury. J Transl Med. 2023;21:179 pubmed publisher
	Zhong W, Liu T, Yang H, Duan J, Yang J, Guan X, et al. TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury. Int J Biol Sci. 2023;19:242-257 pubmed publisher
	Sawaya A, Stone R, Mehdizadeh S, Pastar I, Worrell S, Balukoff N, et al. FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers. EMBO Rep. 2022;23:e54558 pubmed publisher
	Seo D, Che X, Kim S, Kim D, Ma H, Kim J, et al. Triggering Receptor Expressed on Myeloid Cells-1 Agonist Regulates Intestinal Inflammation via Cd177+ Neutrophils. Front Immunol. 2021;12:650864 pubmed publisher
	Deng Q, Yang S, Sun L, Dong K, Li Y, Wu S, et al. Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin-ferroportin axis. Gut Microbes. 2021;13:1-18 pubmed publisher
	Vandestienne M, Zhang Y, Santos Zas I, Al Rifai R, Joffre J, Giraud A, et al. TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm. J Clin Invest. 2021;131: pubmed publisher
	Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, et al. Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. PLoS Pathog. 2019;15:e1007907 pubmed publisher
	Lee Y, Yeo I, Kim K, Han S, Hong J. Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity. Front Immunol. 2019;10:1379 pubmed publisher
	Baruah S, Murthy S, Keck K, Galvan I, Prichard A, Allen L, et al. TREM-1 regulates neutrophil chemotaxis by promoting NOX-dependent superoxide production. J Leukoc Biol. 2019;105:1195-1207 pubmed publisher
	Yuan Z, Fan X, Staitieh B, Bedi C, Spearman P, Guidot D, et al. HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1. Sci Rep. 2017;7:42028 pubmed publisher
	Wu K, Byers D, Jin X, Agapov E, Alexander Brett J, Patel A, et al. TREM-2 promotes macrophage survival and lung disease after respiratory viral infection. J Exp Med. 2015;212:681-97 pubmed publisher
	Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, et al. TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog. 2014;10:e1003900 pubmed publisher
	Ingersoll M, Spanbroek R, Lottaz C, Gautier E, Frankenberger M, Hoffmann R, et al. Comparison of gene expression profiles between human and mouse monocyte subsets. Blood. 2010;115:e10-9 pubmed publisher
	Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, et al. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol. 2009;183:2027-36 pubmed publisher

image

image 1 :

Detection of TREM-1 antibody in Mouse Splenocytes antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

MAB1187

SKU :

MAB1187-100

product name :

TREM-1 Antibody

description :

The Mouse TREM-1 Antibody from R&D Systems is a rat monoclonal antibody to TREM1. This antibody reacts with mouse. The Mouse TREM-1 Antibody has been validated for the following applications: Western Blot,Agonist Activity,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Neutralization,Immunocytochemistry,Functional Assay,ELISA Capture.

target :

TREM-1

unit size :

100 ug (also 25 ug, 500 ug)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

174031

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse TREM-1, Ala21-Ser202, Accession # Q9JKE2

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse TREM-1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse TREM-2B, recombinant human (rh) TREM-1, or rhTREM-2 is observed.

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

gene symbol :

TREM1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

Q9JKE2

applications :

Western Blot,Agonist Activity,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Neutralization,Immunocytochemistry,Functional Assay,ELISA Capture

product keywords :

MAB1187, mTREM-1 MAb Cl 174031, Rat Anti-Mouse TREM-1 Monoclonal Antibody, Anti-TREM-1, Rat Anti Mouse TREM-1 Monoclonal Antibody, Anti-mTREM-1, TREM1, TREM 1, Immunoglobulin SF, IgSF, sTREM-1

USD :

469

USD 2025 :

469 USD

alt names :

CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1

more info or order :

R&D Systems product webpage