product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-18 R▀/IL-1 R7 Antibody
catalog :
MAB1181
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
132016
reactivity :
human
application :
western blot, neutralization, flow cytometry
more info or order :
citations: 4
Reference
Hedl M, Zheng S, Abraham C. The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. J Immunol. 2014;192:5924-32 pubmed publisher
Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, et al. Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res Ther. 2011;13:R52 pubmed publisher
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, et al. CD molecules 2006--human cell differentiation molecules. J Immunol Methods. 2007;319:1-5 pubmed
Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, et al. IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. J Immunol. 2003;170:5571-7 pubmed
product information
master code :
MAB1181
SKU :
MAB1181
product name :
Human IL-18 R▀/IL-1 R7 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human IL-18 Rß/IL-1 R7 Antibody from R&D Systems is a mouse monoclonal antibody to IL-18 R beta/IL-1 R7/ACPL. This antibody reacts with human. The Human IL-18 Rß/IL-1 R7 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization.
target :
IL-18 R beta/IL-1 R7
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
132016
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-18 R▀/IL-1 R7, Met1-Arg356, Accession # O95256
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-18 R▀/IL-1 R7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse IL-18 R▀, recombinant human (rh) IL-18 R, rhIL-1 RI, rhIL-1 RII, rhIL-1 RAcP, and rhIL-1 Rrp2 is observed.
gene symbol :
IL18RAP
top caption :
IFN-? secretion Induced by IL-18/IL1F4 and Neutralization by Human IL-18 Rss/IL-1 R7 Antibody.
accessionNumbers :
O95256
applications :
Flow Cytometry,Western Blot,Neutralization
USD :
569 USD
alt names :
Accessory protein-like, AcPL, CD218 antigen-like family member B, CD218b, CD218b antigen, CDw218b, IL-1 R7, IL-18 receptor accessory protein, IL-18 receptor beta, IL18R beta, IL-18RAcP, IL18RAP, IL-18Rb, IL18RB, IL-18Rbeta, IL-18R-beta, IL-1R accessory protein-like, IL1R7, IL-1R7, IL-1R-7, IL-1RAcPL, interleukin 18 receptor accessory protein, Interleukin-1 receptor 7, interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, MGC120589, MGC120590
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.