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company name :
R&D Systems
product type :
antibody
product name :
Human Prolactin R Antibody
catalog :
MAB1167
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
250448
reactivity :
human
application :
western blot, neutralization
more info or order :
citations: 7
Reference
Chen J, Yin T, Hu X, Chang L, Sang Y, Xu L, et al. CD36-mediated arachidonic acid influx from decidual stromal cells increases inflammatory macrophages in miscarriage. Cell Rep. 2024;43:114881 pubmed publisher
Mart xed nez Albert E, Lutz N, H xfc bener R, Dimitrov S, Lange T, Born J, et al. Sleep promotes T-cell migration towards CCL19 via growth hormone and prolactin signaling in humans. Brain Behav Immun. 2024;118:69-77 pubmed publisher
Nie H, Huang P, Jiang S, Yang Q, Hu L, Yang X, et al. The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer. Theranostics. 2021;11:3898-3915 pubmed publisher
Linher Melville K, Singh G. The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells. BMC Cancer. 2014;14:415 pubmed publisher
Lopez Pulido E, Muñoz Valle J, Del Toro Arreola S, Jave Suarez L, Bueno Topete M, Estrada Chávez C, et al. High expression of prolactin receptor is associated with cell survival in cervical cancer cells. Cancer Cell Int. 2013;13:103 pubmed publisher
López Rincón G, Pereira Suárez A, Del Toro Arreola S, Sanchez Hernandez P, Ochoa Zarzosa A, Muñoz Valle J, et al. Lipopolysaccharide induces the expression of an autocrine prolactin loop enhancing inflammatory response in monocytes. J Inflamm (Lond). 2013;10:24 pubmed publisher
Kanda N, Watanabe S. Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. Endocrinology. 2007;148:2317-25 pubmed
product information
master code :
MAB1167
SKU :
MAB1167
product name :
Human Prolactin R Antibody
unit size :
500 ug (also 25 ug)
description :
The Human Prolactin R Antibody from R&D Systems is a mouse monoclonal antibody to Prolactin R. This antibody reacts with human. The Human Prolactin R Antibody has been validated for the following applications: Neutralization,Western Blot.
target :
Prolactin R
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
250448
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Prolactin R, Gln25-Asp234, Accession # P16471
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Prolactin R in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Prolactin R and recombinant rat Prolactin R is observed.
gene symbol :
PRLR
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Prolactin R Inhibition of Prolactin-dependent Cell Proliferation and Neutralization by Human Prolactin R Antibody.
accessionNumbers :
P16471
applications :
Neutralization,Western Blot
USD :
569 USD
alt names :
delta 4-delta 7/11 truncated prolactin receptor, delta 4-SF1b truncated prolactin receptor, hPRL receptor, hPRLrI, PRLR, PRL-R, prolactin receptor, prolactin receptor delta 7/11, ProlactinR, secreted prolactin binding protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.