CD8 Antibody | R&D Systems MAB116-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CD8 Antibody

catalog :

MAB116-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

448 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

53-6.7

reactivity :

mouse

application :

immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 2 ug/ml; loading ...; fig 3e	Break T, Oikonomou V, Dutzan N, Desai J, Swidergall M, Freiwald T, et al. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021;371: pubmed publisher
	Xu Y, Lv L, Liu Y, Smith M, Li W, Tan X, et al. Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy. J Clin Invest. 2019;130: pubmed publisher
	Zhang S, Zhong M, Wang C, Xu Y, Gao W, Zhang Y. CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer. Cell Death Dis. 2018;9:766 pubmed publisher
	Wiehagen K, Girgis N, Yamada D, Smith A, Chan S, Grewal I, et al. Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity. Cancer Immunol Res. 2017;5:1109-1121 pubmed publisher
	Tanaka R, Goshima F, Esaki S, Sato Y, Murata T, Nishiyama Y, et al. The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacarbazine in a mouse melanoma model. Am J Cancer Res. 2017;7:1693-1703 pubmed
	Shapiro M, Nandi B, Gonzalez G, Prabhala R, Mashimo H, Huang Q, et al. Deficiency of the immunostimulatory cytokine IL-21 promotes intestinal neoplasia via dysregulation of the Th1/Th17 axis. Oncoimmunology. 2017;6:e1261776 pubmed publisher
	Zhang H, Chin A. Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. PLoS ONE. 2014;9:e94793 pubmed publisher
	Hokeness K, Deweerd E, Munks M, Lewis C, Gladue R, Salazar Mather T. CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection. J Virol. 2007;81:1241-50 pubmed

image

image 1 :

CD8a antibody in Mouse Splenocytes by Immunocytochemistry (ICC).

product information

brand :

R&D Systems

master code :

MAB116

SKU :

MAB116-100

product name :

CD8 Antibody

description :

The Mouse CD8 alpha Antibody from R&D Systems is a rat monoclonal antibody to CD8. This antibody reacts with mouse. The Mouse CD8 alpha Antibody has been validated for the following applications: Flow Cytometry, Immunoprecipitation, Cell depletion, Inhibition of T Cell Function, Immunocytochemistry, CyTOF-ready.

target :

CD8

category :

Primary Antibodies

sizes available :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

53-6.7

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse thymus or spleen

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects both the alpha and alpha ' chains of mouse CD8 (1)

gene symbol :

CD8A

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunoprecipitation, Cell depletion, Inhibition of T Cell Function, Immunocytochemistry, CyTOF-ready

USD :

448 USD

alt names :

CD_antigen: CD8a, CD8, CD8 antigen, alpha polypeptide (p32), CD8A, CD8a molecule, LEU2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage