Human Galectin-3 Antibody | R&D Systems MAB1154 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Galectin-3 Antibody

catalog :

MAB1154

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

194804

reactivity :

human

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Li S, Pritchard D, Yu L. Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells. Cell Death Dis. 2023;14:268 pubmed publisher
Colomb F, Wang W, Simpson D, Zafar M, Beynon R, Rhodes J, et al. Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J Biol Chem. 2017;292:8381-8389 pubmed publisher
Yang H, Yin J, Ficarrotta K, Hsu S, Zhang W, Cheng C. Aberrant expression and hormonal regulation of Galectin-3 in endometriosis women with infertility. J Endocrinol Invest. 2016;39:785-91 pubmed publisher
Suzuki O, Hirsch B, Abe M, Dürkop H, Stein H. Galectin-1-mediated cell death is increased by CD30-induced signaling in anaplastic large cell lymphoma cells but not in Hodgkin lymphoma cells. Lab Invest. 2012;92:191-9 pubmed publisher
Spivey K, Chung I, Banyard J, Adini I, Feldman H, Zetter B. A role for collagen XXIII in cancer cell adhesion, anchorage-independence and metastasis. Oncogene. 2012;31:2362-72 pubmed publisher
Papaspyridonos M, McNeill E, de Bono J, Smith A, Burnand K, Channon K, et al. Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction. Arterioscler Thromb Vasc Biol. 2008;28:433-40 pubmed

product information

master code :

MAB1154

SKU :

MAB1154

product name :

Human Galectin-3 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human Galectin-3 Antibody from R&D Systems is a mouse monoclonal antibody to Galectin-3. This antibody reacts with human. The Human Galectin-3 Antibody has been validated for the following applications: Immunocytochemistry,Flow Cytometry,Western Blot.

target :

Galectin-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

194804

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Galectin-3, Ala2-Ile250, Accession # P17931

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Galectin-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows 100% cross-reactivity with recombinant mouse Galectin-3 and no cross-reactivity with rhGalectin-1, -2 -4, -7, or -8.

gene symbol :

LGALS3

top caption :

Detection of Human Galectin-3 antibody by Western Blot.

accessionNumbers :

P17931

applications :

Flow Cytometry,Western Blot

USD :

559 USD

alt names :

AGE-R3, Carbohydrate-binding protein 35, CBP 35,35 kDa lectin, CBP35, Gal-3, GAL3, galactin-3, Galactose-specific lectin 3, Galactoside-binding protein, GALBPCBP35, galectin-3, Galectin3, GALIG, IgE-binding protein, L29, L31, L-31, Laminin-binding protein, Lectin L-29, lectin, galactoside-binding, soluble, 3, LGALS2, LGALS3, Mac-2, Mac-2 antigen, MAC2GAL3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage