Human RAGE Antibody | R&D Systems MAB11451 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human RAGE Antibody

catalog :

MAB11451

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

176902

reactivity :

human

application :

western blot, ELISA

citations: 11

Reference
Rolfes V, Ribeiro L, Hawwari I, Böttcher L, Rosero N, Maasewerd S, et al. Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Rep. 2020;31:107615 pubmed publisher
Wu J, Deng Z, Sun M, Zhang W, Yang Y, Zeng Z, et al. Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation. Lab Invest. 2019;: pubmed publisher
Pickering R, Tikellis C, Rosado C, Tsorotes D, Dimitropoulos A, SMITH M, et al. Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis. J Clin Invest. 2019;129:406-421 pubmed publisher
Zhou B, Flodby P, Luo J, Castillo D, Liu Y, Yu F, et al. Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis. J Clin Invest. 2018;128:970-984 pubmed publisher
Robert J, Button E, Stukas S, Boyce G, Gibbs E, Cowan C, et al. High-density lipoproteins suppress A?-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture. Mol Neurodegener. 2017;12:60 pubmed publisher
Liu W, Shen T, Chen R, Wu H, Wang Y, Deng J, et al. Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy. J Biol Chem. 2015;290:20499-510 pubmed publisher
Tuinman P, Cornet A, Kuipers M, Vlaar A, Schultz M, Beishuizen A, et al. Soluble receptor for advanced glycation end products as an indicator of pulmonary vascular injury after cardiac surgery. BMC Pulm Med. 2013;13:76 pubmed publisher
Yamakawa N, Uchida T, Matthay M, Makita K. Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011;300:L516-25 pubmed publisher
Tam H, Shiu S, Wong Y, Chow W, Betteridge D, Tan K. Effects of atorvastatin on serum soluble receptors for advanced glycation end-products in type 2 diabetes. Atherosclerosis. 2010;209:173-7 pubmed publisher
Sakaguchi M, Sonegawa H, Murata H, Kitazoe M, Futami J, Kataoka K, et al. S100A11, an dual mediator for growth regulation of human keratinocytes. Mol Biol Cell. 2008;19:78-85 pubmed
Zen K, Chen C, Chen Y, Wilton R, Liu Y. Receptor for advanced glycation endproducts mediates neutrophil migration across intestinal epithelium. J Immunol. 2007;178:2483-90 pubmed

product information

brand :

R&D Systems

master code :

MAB11451

SKU :

MAB11451-100

product name :

Human RAGE Antibody

description :

The Human RAGE Antibody from R&D Systems is a mouse monoclonal antibody to AGER. This antibody reacts with human. The Human RAGE Antibody has been validated for the following applications: Western Blot, Blockade of Receptor-ligand Interaction, ELISA Capture (Matched Antibody Pair).

target :

AGER

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

176902

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human RAGE, Gln24-Ala344, Accession # Q15109

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human RAGE in ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse RAGE and recombinant rat RAGE is observed.

gene symbol :

AGER

endotoxin note :

<0.01 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB11451

accessionNumbers :

Q15109

applications :

Western Blot, Blockade of Receptor-ligand Interaction, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

advanced glycosylation end product-specific receptor, AGER, RAGE isoform delta, RAGE isoform sRAGE-delta, Receptor for advanced glycosylation end products, receptor for advanced glycosylation end-products, SCARJ1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.