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company name :
R&D Systems
product type :
antibody
product name :
Mouse CD45 Antibody
catalog :
MAB114-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
30-F11
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5b
Baik J, Park H, Kataru R, Savetsky I, Ly C, Shin J, et al. TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation. Clin Transl Med. 2022;12:e758 pubmed publisher
Song J, Deshpande T, Zhang X, Hannocks M, Lycke N, Cardell S, et al. The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation. iScience. 2023;26:106753 pubmed publisher
Roy T, Banang Mbeumi S, Boateng S, Ruiz E, Chamcheu R, Kang L, et al. Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation. Front Immunol. 2022;13:1075804 pubmed publisher
Lima C, Maleski A, Bernardo J, Zelli V, Komegae E, Lopes Ferreira M. TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model. Front Immunol. 2022;13:857692 pubmed publisher
Akazawa Y, Taneike M, Ueda H, Kitazume Taneike R, Murakawa T, Sugihara R, et al. Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload. Sci Rep. 2022;12:41 pubmed publisher
Hammer S, Vieira C, McFarland D, Sandler M, Levitsky Y, Dorweiler T, et al. Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction. Diabetologia. 2021;64:1674-1689 pubmed publisher
Chlipala E, Butters M, Brous M, Fortin J, Archuletta R, Copeland K, et al. Impact of Preanalytical Factors During Histology Processing on Section Suitability for Digital Image Analysis. Toxicol Pathol. 2021;49:755-772 pubmed publisher
Wortmann M, Arshad M, Hakimi M, B xf6 ckler D, Dihlmann S. Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms. Mol Med. 2020;26:87 pubmed publisher
Jeong S, Cho M, Ko N, Kim S, Jung I, Min J, et al. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm. Exp Mol Med. 2020;52:1587-1601 pubmed publisher
Omiya S, Omori Y, Taneike M, Murakawa T, Ito J, Tanada Y, et al. Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts. Circulation. 2020;141:667-677 pubmed publisher
Kataru R, Ly C, Shin J, Park H, Baik J, Rehal S, et al. Tumor lymphatic function regulates tumor inflammatory and immunosuppressive microenvironments. Cancer Immunol Res. 2019;: pubmed publisher
Ly C, Nores G, Kataru R, Mehrara B. T helper 2 differentiation is necessary for development of lymphedema. Transl Res. 2019;206:57-70 pubmed publisher
García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed publisher
Beli E, Yan Y, Moldovan L, Vieira C, Gao R, Duan Y, et al. Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes. 2018;67:1867-1879 pubmed publisher
Mantani P, Dunér P, Bengtsson E, Ljungcrantz I, Sundius L, To F, et al. Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice. J Biol Chem. 2018;293:6791-6801 pubmed publisher
Elia L, Kunderfranco P, Carullo P, Vacchiano M, Farina F, Hall I, et al. UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease. J Clin Invest. 2018;128:2473-2486 pubmed publisher
Ando T, Kashiwakura J, Itoh Nagato N, Yamashita H, Baba M, Kawakami Y, et al. Histamine-releasing factor enhances food allergy. J Clin Invest. 2017;127:4541-4553 pubmed publisher
Wiehagen K, Girgis N, Yamada D, Smith A, Chan S, Grewal I, et al. Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity. Cancer Immunol Res. 2017;5:1109-1121 pubmed publisher
Komegae E, Souza T, Grund L, Lima C, Lopes Ferreira M. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis. PLoS ONE. 2017;12:e0171796 pubmed publisher
Bignami F, Lorusso A, Rama P, Ferrari G. Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment. Acta Ophthalmol. 2017;95:e641-e648 pubmed publisher
Omiya S, Omori Y, Taneike M, Protti A, Yamaguchi O, Akira S, et al. Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation. Am J Physiol Heart Circ Physiol. 2016;311:H1485-H1497 pubmed publisher
Gardenier J, Hespe G, Kataru R, Savetsky I, Torrisi J, Nores G, et al. Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema. JCI Insight. 2016;1:e84095 pubmed publisher
Fink S, Myeroff L, Kariv R, Platzer P, Xin B, Mikkola D, et al. Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival. Oncotarget. 2015;6:30500-15 pubmed publisher
Gordon W, Zeller M, Klein R, Swindell W, Ho H, Espetia F, et al. A GRHL3-regulated repair pathway suppresses immune-mediated epidermal hyperplasia. J Clin Invest. 2014;124:5205-18 pubmed publisher
Kanapathippillai P, Hedberg A, Fenton C, Fenton K. Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis. Cytokine. 2013;62:244-52 pubmed publisher
Mills J, Alabanza L, Mahamed D, Bynoe M. Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis. J Neuroinflammation. 2012;9:193 pubmed
Carter A, Aggarwal M, Kopia G, Tio F, Tsao P, Kolata R, et al. Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model. Cardiovasc Res. 2004;63:617-24 pubmed
product information
brand :
R&D Systems
master code :
MAB114
SKU :
MAB114-100
product name :
Mouse CD45 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse CD45 Antibody from R&D Systems is a rat monoclonal antibody to CD45. This antibody reacts with human,mouse,porcine. The Mouse CD45 Antibody has been validated for the following applications: Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunoprecipitation,Complement-dependent Cytotoxicity,CyTOF-reported.
target :
CD45
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
30-F11
conjugate :
Unconjugated
dilution :
Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-25 ug/mL, Immunoprecipitation, Complement-dependent Cytotoxicity, Immunocytochemistry 3-25 ug/mL, CyTOF-reported
host :
Rat
immunogen :
Mouse thymus and spleen cells
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Porcine
specificity :
Detects mouse CD45. Recognizes all CD45 isoforms as well as the known mouse CD45 alloantigens (CD45-1/Ly 5a and CD45-2/Ly 5b) (15).
gene symbol :
PTPRC
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
applications :
Immunoprecipitation,Complement-dependent Cytotoxicity,CyTOF-reported,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
479 USD
alt names :
B220, CD_antigen: CD45, CD45, CD45 antigen, CD45R, EC 3.1.3.48, EC:3.1.3.48, GP180, LCA, L-CA, Leukocyte common antigen, LY5, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.