Human Siglec-3/CD33 Antibody | R&D Systems MAB1137-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Siglec-3/CD33 Antibody

catalog :

MAB1137-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6C5/2

reactivity :

human

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Tsai T, Huang M, Sung P, Peng C, Tao M, Yang H, et al. SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection. J Clin Invest. 2021;131: pubmed publisher
Ishida A, Akita K, Mori Y, Tanida S, Toda M, Inoue M, et al. Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33. J Biol Chem. 2014;289:25341-50 pubmed publisher
Kudo Saito C, Yura M, Yamamoto R, Kawakami Y. Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res. 2014;74:1361-70 pubmed publisher

product information

master code :

MAB1137

SKU :

MAB1137-100

product name :

Human Siglec-3/CD33 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Siglec-3/CD33 Antibody from R&D Systems is a mouse monoclonal antibody to Siglec-3/CD33. This antibody reacts with human. The Human Siglec-3/CD33 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Western Blot,CyTOF-ready.

target :

Siglec-3/CD33

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

6C5/2

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant human Siglec-3/CD33, Extracellular domain

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Siglec-3/CD33 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Siglec-2, -5, -7, or -9 is observed.

gene symbol :

CD33

top caption :

Detection of Siglec-3/CD33 antibody in Human Blood Granulocytes antibody by Flow Cytometry.

applications :

Flow Cytometry,Neutralization,Western Blot,CyTOF-ready

USD :

469 USD

alt names :

CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, gp67, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, Siglec3, SIGLEC-3, SIGLEC3gp67

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage