product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Rae-1 epsilon Antibody
catalog :
MAB1135-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
205001
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 5
Reference
Kavazović I, Lenartic M, Jelencic V, Jurkovic S, Lemmermann N, Jonjic S, et al. NKG2D stimulation of CD8+ T cells during priming promotes their capacity to produce cytokines in response to viral infection in mice. Eur J Immunol. 2017;47:1123-1135 pubmed publisher
Lin Z, Wang C, Xia H, Liu W, Xiao W, Qian L, et al. CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1? transgenic mice. Immunology. 2014;141:401-15 pubmed publisher
Jung H, Hsiung B, Pestal K, Procyk E, Raulet D. RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med. 2012;209:2409-22 pubmed publisher
Markiewicz M, Wise E, Buchwald Z, Pinto A, Zafirova B, Polic B, et al. RAE1? ligand expressed on pancreatic islets recruits NKG2D receptor-expressing cytotoxic T cells independent of T cell receptor recognition. Immunity. 2012;36:132-41 pubmed publisher
Unni A, Bondar T, Medzhitov R. Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A. 2008;105:1686-91 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1135
SKU :
MAB1135-100
product name :
Mouse Rae-1 epsilon Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse Rae-1 epsilon Antibody from R&D Systems is a rat monoclonal antibody to Rae-1 epsilon. This antibody reacts with mouse. The Mouse Rae-1 epsilon Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry-Frozen,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
Rae-1 epsilon
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
205001
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 2.5 ug/10^6 cells, Blockade of Receptor-ligand Interaction, CyTOF-ready
host :
Rat
immunogen :
BaF3 mouse pro-B cell line transfected with mouse Rae-1 epsilon
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse Rae-1 epsilon in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Rae-1 alpha , ▀, gamma , or delta is observed. By flow cytometry, no cross-reactivity with mouse Rae-1 alpha or mouse Rae-1 gamma .
gene symbol :
Raet1e
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Rae-1e antibody in BaF3 Mouse Cell Line Transfected with Mouse Rae-1e and eGFP antibody by Flow Cytometry.
applications :
Blockade of Receptor-ligand Interaction,CyTOF-ready,Flow Cytometry,Immunohistochemistry-Frozen
USD :
469 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.