Human ErbB4/Her4 Antibody | R&D Systems MAB11311 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ErbB4/Her4 Antibody

catalog :

MAB11311

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

182818

reactivity :

human

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Khan T, Seddon A, Dalgleish A, Khelwatty S, Ioannou N, Mudan S, et al. Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancr. Oncol Rep. 2020;44:2581-2594 pubmed publisher
Puvanenthiran S, Essapen S, Seddon A, Modjtahedi H. Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs. Int J Oncol. 2016;49:1825-1838 pubmed publisher
Ioannou N, Seddon A, Dalgleish A, Mackintosh D, Solca F, Modjtahedi H. Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition. Int J Oncol. 2016;48:908-18 pubmed publisher
Zomerman W, Plasschaert S, Diks S, Lourens H, Meeuwsen de Boer T, Hoving E, et al. Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines. PLoS ONE. 2015;10:e0141381 pubmed publisher
Ioannou N, Dalgleish A, Seddon A, Mackintosh D, Guertler U, Solca F, et al. Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells. Br J Cancer. 2011;105:1554-62 pubmed publisher
Khelwatty S, Essapen S, Seddon A, Modjtahedi H. Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members. Int J Oncol. 2011;39:483-91 pubmed publisher

product information

master code :

MAB11311

SKU :

MAB11311

product name :

Human ErbB4/Her4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human ErbB4/Her4 Antibody from R&D Systems is a mouse monoclonal antibody to ErbB4/Her4. This antibody reacts with human. The Human ErbB4/Her4 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,CyTOF-ready.

target :

ErbB4/Her4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

182818

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ErbB4/Her4, Glu26-Arg649, Accession # Q15303

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human ErbB4/Her4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) EGF R, rhErbB2, or rhErbB3 is observed.

gene symbol :

ERBB4

accessionNumbers :

Q15303

applications :

Flow Cytometry,Western Blot,CyTOF-ready

USD :

479 USD

alt names :

avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, EC 2.7.10, EC 2.7.10.1, HER4, HER4MGC138404, p180erbB4, Proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4, v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage