product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Neprilysin/CD10 Antibody
catalog :
MAB1126
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
200103
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
R&D Systems product webpage
citations: 6
Reference
Leader A, Grout J, Maier B, Nabet B, Park M, Tabachnikova A, et al. Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification. Cancer Cell. 2021;39:1594-1609.e12 pubmed publisher
Lu M, Ji W, Chen H, Sun Y, Zhao X, Wang F, et al. Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model. Front Aging Neurosci. 2021;13:650103 pubmed publisher
Khan M, Shin J, Kim M, Shin T, Kim J. Green Tea Seed Isolated Theasaponin E1 Ameliorates AD Promoting Neurotoxic Pathogenesis by Attenuating Aβ Peptide Levels in SweAPP N2a Cells. Molecules. 2020;25: pubmed publisher
Kulas J, Puig K, Combs C. Amyloid precursor protein in pancreatic islets. J Endocrinol. 2017;235:49-67 pubmed publisher
Pacheco Quinto J, Eckman C, Eckman E. Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex. Neurobiol Aging. 2016;48:83-92 pubmed publisher
Chen P, Chen Z, Hou W, Yu L, Chen R. Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease. Sci Rep. 2016;6:29760 pubmed publisher
product information
master code :
MAB1126
SKU :
MAB1126
product name :
Human/Mouse Neprilysin/CD10 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human/Mouse Neprilysin/CD10 Antibody from R&D Systems is a rat monoclonal antibody to Neprilysin/CD10. This antibody reacts with human,mouse. The Human/Mouse Neprilysin/CD10 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot.
target :
Neprilysin/CD10
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
200103
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Neprilysin/CD10, Tyr52-Trp750, Accession # Q61391
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human and mouse Neprilysin/CD10 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human ECE-2 or recombinant mouse Kell is observed.
gene symbol :
MME
top caption :
Neprilysin/CD10 antibody in Human Kidney by Immunohistochemistry (IHC-P).
accessionNumbers :
Q61391
applications :
Immunohistochemistry,Western Blot
USD :
559 USD
alt names :
Atriopeptidase, CALLA, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10, CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, Leu-19, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, MME, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral Endopeptidase 24.11, NKH1, SFE, Skin fibroblast elastase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.