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company name :
R&D Systems
product type :
antibody
product name :
Mouse TER-119 Antibody
catalog :
MAB1125
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
TER-119
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 25
Reference
Halder S, Sapkota A, Milner R. β1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter. Acta Neuropathol Commun. 2024;12:45 pubmed publisher
Halder S, Milner R. Spinal Cord Blood Vessels in Aged Mice Show Greater Levels of Hypoxia-Induced Vascular Disruption and Microglial Activation. Int J Mol Sci. 2023;24: pubmed publisher
Ichiyama Y, Matsumoto R, Obata S, Sawada O, Saishin Y, Kakinoki M, et al. Assessment of mouse VEGF neutralization by ranibizumab and aflibercept. PLoS ONE. 2022;17:e0278951 pubmed publisher
Watanabe C, Shibuya H, Ichiyama Y, Okamura E, Tsukiyama Fujii S, Tsukiyama T, et al. Essential Roles of Exocyst Complex Component 3-like 2 on Cardiovascular Development in Mice. Life (Basel). 2022;12: pubmed publisher
Zhao B, Ni Y, Zhang H, Zhao Y, Li L. Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression. Cell Death Discov. 2022;8:429 pubmed publisher
Maeso Alonso L, Alonso Olivares H, Mart xed nez Garc xed a N, L xf3 pez Ferreras L, Villoch Fern xe1 ndez J, Puente Santamar xed a L, et al. p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin. Cell Mol Life Sci. 2022;79:535 pubmed publisher
Ando T, Tai Nagara I, Sugiura Y, Kusumoto D, Okabayashi K, Kido Y, et al. Tumor-specific interendothelial adhesion mediated by FLRT2 facilitates cancer aggressiveness. J Clin Invest. 2022;132: pubmed publisher
Yu R, Kim N, Li Y, Jeong J, Park S, Zhou B, et al. Vascular Sema3E-Plexin-D1 Signaling Reactivation Promotes Post-stroke Recovery through VEGF Downregulation in Mice. Transl Stroke Res. 2022;13:142-159 pubmed publisher
Tai Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nat Commun. 2020;11:6314 pubmed publisher
Schlüter A, Aksan B, Diem R, Fairless R, Mauceri D. VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury. Mol Ther Methods Clin Dev. 2020;17:281-299 pubmed publisher
Bálint L, Ocskay Z, Deák B, Aradi P, Jakus Z. Lymph Flow Induces the Postnatal Formation of Mature and Functional Meningeal Lymphatic Vessels. Front Immunol. 2019;10:3043 pubmed publisher
Luxan G, Stewen J, Díaz N, Kato K, Maney S, Aravamudhan A, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. elife. 2019;8: pubmed publisher
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed publisher
Jensen L, Hot B, Ramsköld D, Germano R, Yokota C, Giatrellis S, et al. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling. Arterioscler Thromb Vasc Biol. 2019;39:1432-1447 pubmed publisher
Neto F, Klaus Bergmann A, Ong Y, Alt S, Vion A, Szymborska A, et al. YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development. elife. 2018;7: pubmed publisher
Palmieri E, Menga A, Martín Pérez R, Quinto A, Riera Domingo C, De Tullio G, et al. Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis. Cell Rep. 2017;20:1654-1666 pubmed publisher
Li S, Nih L, Bachman H, Fei P, Li Y, Nam E, et al. Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability. Nat Mater. 2017;16:953-961 pubmed publisher
Stantzou A, Schirwis E, Swist S, Alonso Martin S, Polydorou I, Zarrouki F, et al. BMP signaling regulates satellite cell-dependent postnatal muscle growth. Development. 2017;144:2737-2747 pubmed publisher
Tai Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, et al. Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development. 2017;144:2392-2401 pubmed publisher
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed publisher
Ramasamy S, Kusumbe A, Schiller M, Zeuschner D, Bixel M, Milia C, et al. Blood flow controls bone vascular function and osteogenesis. Nat Commun. 2016;7:13601 pubmed publisher
Gong H, An S, Sassmann A, Liu M, Mastej V, Mittal M, et al. PAR1 Scaffolds TGF?RII to Downregulate TGF-? Signaling and Activate ESC Differentiation to Endothelial Cells. Stem Cell Reports. 2016;7:1050-1058 pubmed publisher
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Arnold T, Ferrero G, Qiu H, Phan I, Akhurst R, Huang E, et al. Defective retinal vascular endothelial cell development as a consequence of impaired integrin ?V?8-mediated activation of transforming growth factor-?. J Neurosci. 2012;32:1197-206 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB1125
SKU :
MAB1125
product name :
Mouse TER-119 Antibody
unit size :
500 ug (also 25 ug)
seo description :
The Mouse TER-119 Antibody from R&D Systems is a rat monoclonal antibody to TER-119. This antibody reacts with mouse. The Mouse TER-119 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Western Blot,CyTOF-reported.
target :
TER-119
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
TER-119
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation, CyTOF-reported
host :
Rat
immunogen :
C57BL/6 mouse day-14 fetal liver cells
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse TER-119 in Western blots. This antibody has been shown to react with cells of the erythroid lineage in embryonic yolk sac, fetal liver, adult bone marrow, adult peripheral blood, and adult lymphoid organs (Ikuta, K. et al. (1990) Cell 62 :863). TER-119 Antigen is a molecule associated with cell-surface glycophorin A (Kina, T. et al. (2000) Br. J. Haematol. 109 :280). The antibody has been shown to react with erythroid cells at differentiation stages from early proerythroblast to mature erythrocyte (Kina, T. et al. (2000) Br. J. Haematol. 109 :280).
gene symbol :
Ly76
applications :
Flow Cytometry,Immunoprecipitation,Western Blot,CyTOF-reported,Immunohistochemistry
USD :
569 USD
alt names :
Ly76, Ly-76, TER119
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.