product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CD11b/Integrin alpha M Antibody
catalog :
MAB1124-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M1/70
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 20
Reference
Song J, Deshpande T, Zhang X, Hannocks M, Lycke N, Cardell S, et al. The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation. iScience. 2023;26:106753 pubmed publisher
Raimondi I, Tunesi M, Forloni G, Albani D, Giordano C. 3D brain tissue physiological model with co-cultured primary neurons and glial cells in hydrogels. J Tissue Eng. 2020;11:2041731420963981 pubmed publisher
Subileau M, Acar N, Carret A, Bretillon L, Vilgrain I, Bailly S, et al. Eye lymphatic defects induced by bone morphogenetic protein 9 deficiency have no functional consequences on intraocular pressure. Sci Rep. 2020;10:16040 pubmed publisher
Shi X, Xiao M, Xie Z, Shi Q, Zhang Y, Leavenworth J, et al. Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway. Parasit Vectors. 2020;13:183 pubmed publisher
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, et al. PU.1 controls fibroblast polarization and tissue fibrosis. Nature. 2019;566:344-349 pubmed publisher
Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, et al. Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice. Cell Rep. 2018;24:169-180 pubmed publisher
Zorina Y, Stricker J, Caggiano A, Button D. Human IgM antibody rHIgM22 promotes phagocytic clearance of myelin debris by microglia. Sci Rep. 2018;8:9392 pubmed publisher
Wan S, Sun X, Wu F, Yu Z, Wang L, Lin D, et al. Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensis. J Neuroinflammation. 2018;15:31 pubmed publisher
Zhang H, Li X, Liao S, Wang H, Chen P, Zhu G, et al. SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice. Oncol Rep. 2018;39:358-366 pubmed publisher
Stott S, Hayat S, Carnwath T, Garas S, Sleeman J, Barker R. CD24 expression does not affect dopamine neuronal survival in a mouse model of Parkinson's disease. PLoS ONE. 2017;12:e0171748 pubmed publisher
Busch C, Hendrikx T, Weismann D, Jäckel S, Walenbergh S, Rendeiro A, et al. Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. Hepatology. 2017;65:1181-1195 pubmed publisher
Yin Y, Zhao L, Zhang F, Zhang X. Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. Sci Rep. 2016;6:31874 pubmed publisher
Zhang H, Chin A. Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. PLoS ONE. 2014;9:e94793 pubmed publisher
Mills J, Alabanza L, Mahamed D, Bynoe M. Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis. J Neuroinflammation. 2012;9:193 pubmed
Farini A, Sitzia C, Navarro C, D Antona G, Belicchi M, Parolini D, et al. Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model. Exp Cell Res. 2012;318:1160-74 pubmed publisher
Suzuki M, El Hage N, Zou S, Hahn Y, Sorrell M, Sturgill J, et al. Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death. Mol Neurodegener. 2011;6:78 pubmed publisher
Karpus W, Reynolds N, Behanna H, Van Eldik L, Watterson D. Inhibition of experimental autoimmune encephalomyelitis by a novel small molecular weight proinflammatory cytokine suppressing drug. J Neuroimmunol. 2008;203:73-8 pubmed publisher
Sancho Pelluz J, Wunderlich K, Rauch U, Romero F, van Veen T, Limb G, et al. Sialoadhesin expression in intact degenerating retinas and following transplantation. Invest Ophthalmol Vis Sci. 2008;49:5602-10 pubmed publisher
Spijkers P, da Costa Martins P, Westein E, Gahmberg C, Zwaginga J, Lenting P. LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion. Blood. 2005;105:170-7 pubmed
TEZEL G, Yang X, Yang J, Wax M. Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice. Brain Res. 2004;996:202-12 pubmed
product information
master code :
MAB1124
SKU :
MAB1124-100
product name :
Mouse CD11b/Integrin alpha M Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CD11b/Integrin alpha M Antibody from R&D Systems is a rat monoclonal antibody to CD11b. This antibody reacts with human,mouse,transgenic mouse. The Mouse CD11b/Integrin alpha M Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-reported.
target :
CD11b/Integrin alpha M
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
M1/70
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Con A-activated C57BL/10 splenocytes
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse CD11b/Integrin alpha M. Cross-reaction with human CD11b/Integrin alpha M has been reported (1, 2).
gene symbol :
ITGAM
top caption :
CD11b/Integrin aM antibody in Mouse Splenocytes by Immunocytochemistry (ICC).
applications :
Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-reported
USD :
479 USD
alt names :
antigen CD11b (p170), CD11 antigen-like family member B, CD11b, CD11b antigen, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, CR-3 alpha chain, CR3A, CR3AMGC117044, Integrin alpha M, integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, MAC-1, MAC1A, macrophage antigen alpha polypeptide, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.