product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Netrin-1 Antibody
catalog :
MAB1109-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
158936
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4e
Company V, Andreu Cervera A, Madrigal M, Andrés B, Almagro García F, Chedotal A, et al. Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4e
Schaberg E, Theocharidis U, May M, Lessmann K, Schroeder T, Faissner A. Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells. Front Cell Dev Biol. 2021;9:643060 pubmed publisher
  • western blot; mouse; fig 3e
Robinson R, Griffiths S, van de Haar L, Malinauskas T, van Battum E, Zelina P, et al. Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell. 2021;184:2103-2120.e31 pubmed publisher
Chan E, Ge Y, So Y, Bai Y, Liu L, Wang Y. Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis. Cell Rep. 2022;41:111584 pubmed publisher
Tortereau A, Milhau N, Rhumy E, Castets M, Ponce F, Mehlen P, et al. Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma. Vet Sci. 2022;9: pubmed publisher
Chen J, Schmidt L, Schürger C, Hankir M, Krug S, Rittner H. Netrin-1 as a Multitarget Barrier Stabilizer in the Peripheral Nerve after Injury. Int J Mol Sci. 2021;22: pubmed publisher
Mehrpouya Bahrami P, Miranda K, Singh N, Zumbrun E, Nagarkatti M, Nagarkatti P. Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity. J Biol Chem. 2019;294:7669-7681 pubmed publisher
Méneret A, Franz E, Trouillard O, Oliver T, Zagar Y, Robertson S, et al. Mutations in the netrin-1 gene cause congenital mirror movements. J Clin Invest. 2017;127:3923-3936 pubmed publisher
Dominici C, Moreno Bravo J, Puiggros S, Rappeneau Q, Rama N, Vieugué P, et al. Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Nature. 2017;545:350-354 pubmed publisher
Lahlali T, Plissonnier M, Romero López C, Michelet M, Ducarouge B, Berzal Herranz A, et al. Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response. Cell Mol Gastroenterol Hepatol. 2016;2:281-301.e9 pubmed publisher
Ramkhelawon B, Hennessy E, Ménager M, Ray T, Sheedy F, Hutchison S, et al. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med. 2014;20:377-84 pubmed publisher
Duff G, Argaw A, Cécyre B, Cherif H, Tea N, Zabouri N, et al. Cannabinoid receptor CB2 modulates axon guidance. PLoS ONE. 2013;8:e70849 pubmed publisher
Mancino M, Esposito C, Watanabe K, Nagaoka T, Gonzales M, Bianco C, et al. Neuronal guidance protein Netrin-1 induces differentiation in human embryonal carcinoma cells. Cancer Res. 2009;69:1717-21 pubmed publisher
Lourenço F, Galvan V, Fombonne J, Corset V, Llambi F, Muller U, et al. Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production. Cell Death Differ. 2009;16:655-63 pubmed publisher
product information
master code :
MAB1109
SKU :
MAB1109-100
product name :
Mouse Netrin-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse Netrin-1 Antibody from R&D Systems is a rat monoclonal antibody to Netrin-1. This antibody reacts with canine,human,mouse,rat. The Mouse Netrin-1 Antibody has been validated for the following applications: Knockout Validated,Flow Cytometry,Immunohistochemistry,Immunodepletion,Western Blot,Immunohistochemistry-Frozen.
target :
Netrin-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
158936
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Netrin-1, Val22-Ala603, Accession # AAC52971
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Canine,Human,Mouse,Rat
specificity :
Detects mouse Netrin-1 in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant chicken (rch) Netrin-1 and no cross-reactivity with rchNetrin-2, recombinant human Netrin-4, recombinant mouse (rm) Netrin-4, or rmNetrin-G1a is observed.
gene symbol :
NTN1
top caption :
Detection of Human Netrin-1 by Western Blot
accessionNumbers :
AAC52971
applications :
Flow Cytometry,Immunohistochemistry,Immunodepletion,Western Blot,Immunohistochemistry-Frozen
USD :
469 USD
alt names :
netrin 1, netrin-1, Netrin1, NTN1, NTN1Lnetrin 1, mouse, homolog of
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.