product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IgG Fc Antibody
catalog :
MAB110-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
97924
application :
western blot, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
Kummarapurugu A, Hawkridge A, Ma J, Osei S, Martin R, Zheng S, et al. Neutrophil elastase decreases SARS-CoV-2 spike protein binding to human bronchial epithelia by clipping ACE-2 ectodomain from the epithelial surface. J Biol Chem. 2023;299:104820 pubmed publisher
Mendoza Salazar I, G xf3 mez Castellano K, Gonz xe1 lez Gonz xe1 lez E, Gamboa Suasnavart R, Rodr xed guez Luna S, Santiago Casas G, et al. Anti-SARS-CoV-2 Omicron Antibodies Isolated from a SARS-CoV-2 Delta Semi-Immune Phage Display Library. Antibodies (Basel). 2022;11: pubmed publisher
Miller C, Sagiv Barfi I, Neuh xf6 fer P, Czerwinski D, Artandi S, Bertozzi C, et al. Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression. Cell Chem Biol. 2022;29:451-462.e8 pubmed publisher
Yang M, Zhang G, Wang Y, He M, Xu Q, Lu J, et al. Tumour-associated neutrophils orchestrate intratumoural IL-8-driven immune evasion through Jagged2 activation in ovarian cancer. Br J Cancer. 2020;123:1404-1416 pubmed publisher
Yoon Y, Voloudakis G, Doran N, Zhang E, Dimovasili C, Chen L, et al. PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Mol Psychiatry. 2021;26:1996-2012 pubmed publisher
Chen Q, Liu J, Sawada T, Wei C, Wu S, Han F. Possible role of EphA4 and VEGFR2 interactions in neural stem and progenitor cell differentiation. Exp Ther Med. 2020;19:1789-1796 pubmed publisher
Zhong L, Wang Z, Wang D, Wang Z, Martens Y, Wu L, et al. Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2). Mol Neurodegener. 2018;13:15 pubmed publisher
Mathis T, Housset M, Eandi C, Beguier F, Touhami S, Reichman S, et al. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?. Aging Cell. 2017;16:173-182 pubmed publisher
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, et al. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement. PLoS ONE. 2014;9:e91857 pubmed publisher
Beyer I, van Rensburg R, Strauss R, Li Z, Wang H, Persson J, et al. Epithelial junction opener JO-1 improves monoclonal antibody therapy of cancer. Cancer Res. 2011;71:7080-90 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB110
SKU :
MAB110-100
product name :
Human IgG Fc Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human IgG Fc Antibody from R&D Systems is a mouse monoclonal antibody to IgG. This antibody reacts with human,mouse. The Human IgG Fc Antibody has been validated for the following applications: ELISA Development,Neutralization Control,Western Blot,Control,Neutralization,Flow Cytometry,CyTOF-ready.
target :
IgG
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
97924
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IgG1 Fc region
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects chimeric proteins containing a human IgG Fc region in direct ELISAs and Western blots.
gene symbol :
IGHG1
top caption :
Detection of IgG1 Fc antibody in Human B7-H1/PD-L1 Fc Chimera Bound to HEK293 Human Cell Line Transfected with Human PD-1 and eGFP antibody by Flow Cytometry.
applications :
Flow Cytometry,CyTOF-ready,ELISA Development,Neutralization Control,Western Blot,Control,Neutralization
USD :
479 USD
alt names :
Immunoglobulin G, ImmunoglobulinG
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.