product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Endoglin/CD105 Antibody
catalog :
MAB1097
quantity :
500 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
166709
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry
more info or order :
citations: 4
Reference
Moser V, Workman M, Hurwitz S, Lipman R, Pike C, Svendsen C. Microglial transcription profiles in mouse and human are driven by APOE4 and sex. iScience. 2021;24:103238 pubmed publisher
Walker D, Lue L, Beach T, Tooyama I. Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin. Cells. 2019;8: pubmed publisher
Hawinkels L, Kuiper P, Wiercinska E, Verspaget H, Liu Z, Pardali E, et al. Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. Cancer Res. 2010;70:4141-50 pubmed publisher
Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang Hoover J, et al. Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production. Am J Pathol. 2008;172:1127-40 pubmed publisher
product information
master code :
MAB1097
SKU :
MAB1097
product name :
Human Endoglin/CD105 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human Endoglin/CD105 Antibody from R&D Systems is a mouse monoclonal antibody to Endoglin/CD105. This antibody reacts with human. The Human Endoglin/CD105 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry.
target :
Endoglin/CD105
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
166709
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Endoglin/CD105, Glu26-Gly256, Accession # Q5T9B9
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Endoglin/CD105 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows 10-50% cross-reactivity with recombinant mouse Endoglin.
gene symbol :
ENG
accessionNumbers :
Q5T9B9
applications :
Flow Cytometry,Western Blot,Immunohistochemistry
USD :
499 USD
alt names :
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.