Human PD-1 Antibody | R&D Systems MAB1086-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human PD-1 Antibody

catalog :

MAB1086-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

192106

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Motavalli R, Hosseini M, Soltani Zangbar M, Karimi A, Sadeghi M, Dolati S, et al. Evaluation of the immune checkpoint factors in idiopathic membranous nephropathy. Mol Cell Probes. 2023;69:101914 pubmed publisher
Ludwig N, Hong C, Ludwig S, Azambuja J, Sharma P, Theodoraki M, et al. Isolation and Analysis of Tumor-Derived Exosomes. Curr Protoc Immunol. 2019;127:e91 pubmed publisher
Banga R, Rebecchini C, Procopio F, Noto A, Munoz O, Ioannidou K, et al. Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement. PLoS Pathog. 2019;15:e1007918 pubmed publisher
Shen M, Chen Y, Xu L, Zhu R, Xue X, Tsai Y, et al. Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells. Int J Oncol. 2018;53:317-328 pubmed publisher
Xu L, Ma Q, Zhu J, Li J, Xue B, Gao J, et al. Combined inhibition of JAK1,2/Stat3‑PD‑L1 signaling pathway suppresses the immune escape of castration‑resistant prostate cancer to NK cells in hypoxia. Mol Med Rep. 2018;17:8111-8120 pubmed publisher
Melendreras S, MartÃnez Camblor P, MenÃ©ndez A, Bravo Mendoza C, GonzÃ¡lez Vidal A, Coto E, et al. Soluble co-signaling molecules predict long-term graft outcome in kidney-transplanted patients. PLoS ONE. 2014;9:e113396 pubmed publisher
Daridon C, Loddenkemper C, Spieckermann S, Kuhl A, Salama A, Burmester G, et al. Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Blood. 2012;120:5021-31 pubmed publisher
Sakthivel P, Ramanujam R, Wang X, Pirskanen R, Lefvert A. Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. J Neuroimmunol. 2008;193:149-55 pubmed

product information

master code :

MAB1086

SKU :

MAB1086-100

product name :

Human PD-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human PD-1 Antibody from R&D Systems is a mouse monoclonal antibody to PD-1. This antibody reacts with human. The Human PD-1 Antibody has been validated for the following applications: Western Blot,ELISA Development,Immunohistochemistry-Paraffin.

target :

PD-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

192106

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human PD-1, Leu25-Gln167, Accession # Q8IX89

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human PD-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CD28, rhCTLA4, rhICOS, or recombinant mouse PD-1 is observed.

gene symbol :

PDCD1

top caption :

Detection of Human PD-1 antibody by Western Blot.

accessionNumbers :

Q8IX89

applications :

Western Blot,ELISA Development,Immunohistochemistry-Paraffin

USD :

479 USD

alt names :

CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage