Human Cathepsin V Antibody | R&D Systems MAB1080 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Cathepsin V Antibody

catalog :

MAB1080

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

182016

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Al Hashimi A, Venugopalan V, Rehders M, Sereesongsaeng N, Hein Z, Springer S, et al. Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe. Int J Mol Sci. 2020;21: pubmed publisher
Bergboer J, Tjabringa G, Kamsteeg M, van Vlijmen Willems I, Rodijk Olthuis D, Jansen P, et al. Psoriasis risk genes of the late cornified envelope-3 group are distinctly expressed compared with genes of other LCE groups. Am J Pathol. 2011;178:1470-7 pubmed publisher
Tedelind S, Poliakova K, Valeta A, Hunegnaw R, Yemanaberhan E, Heldin N, et al. Nuclear cysteine cathepsin variants in thyroid carcinoma cells. Biol Chem. 2010;391:923-35 pubmed publisher
Spira D, Stypmann J, Tobin D, Petermann I, Mayer C, Hagemann S, et al. Cell type-specific functions of the lysosomal protease cathepsin L in the heart. J Biol Chem. 2007;282:37045-52 pubmed
Ma D, Yao J, Kuo M, See L, Lin K, Chen S, et al. Generation of endostatin by matrix metalloproteinase and cathepsin from human limbocorneal epithelial cells cultivated on amniotic membrane. Invest Ophthalmol Vis Sci. 2007;48:644-51 pubmed
Cheng T, Hitomi K, van Vlijmen Willems I, de Jongh G, Yamamoto K, Nishi K, et al. Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem. 2006;281:15893-9 pubmed

product information

brand :

R&D Systems

master code :

MAB1080

SKU :

MAB1080

product name :

Human Cathepsin V Antibody

unit size :

500 ug (also 25 ug)

seo description :

The Human Cathepsin V Antibody from R&D Systems is a mouse monoclonal antibody to Cathepsin V. This antibody reacts with human,mouse. The Human Cathepsin V Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation.

target :

Cathepsin V

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

182016

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation 25 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Cathepsin V, Accession # O60911

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human Cathepsin V in direct ELISAs and Western blots. In Western blots, approximately 50% cross-reactivity with recombinant mouse (rm) Cathepsin H and recombinant human (rh) Cathepsin K is observed and no cross-reactivity with rhCathepsin B, C, L, O, S, Z, rmCathepsin B, C, F, or Z is observed.

gene symbol :

CTSL2

accessionNumbers :

O60911

applications :

Immunoprecipitation,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

569 USD

alt names :

cathepsin L2, Cathepsin U, Cathepsin V, CATL2, CTSL2, CTSUcathepsin L2, preproprotein, CTSVMGC125957, EC 3.4.22, EC 3.4.22.43

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage