Human Siglec-5/CD170 Antibody | R&D Systems MAB1072 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Siglec-5/CD170 Antibody

catalog :

MAB1072

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

194117

reactivity :

human, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 5

Reference
Rochereau N, Michaud E, Waeckel L, Killian M, Gayet R, Goguyer Deschaumes R, et al. Essential role of TOSO/FAIM3 in intestinal IgM reverse transcytosis. Cell Rep. 2021;37:110006 pubmed publisher
Alkhodair K, Almhanna H, McGetrick J, Gedair S, Gallagher M, Fernandez Fuertes B, et al. Siglec expression on the surface of human, bull and ram sperm. Reproduction. 2018;155:361-371 pubmed publisher
Ali S, Fong J, Carlin A, Busch T, Linden R, Angata T, et al. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. J Exp Med. 2014;211:1231-42 pubmed publisher
Nordstrom T, Movert E, Olin A, Ali S, Nizet V, Varki A, et al. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein. J Biol Chem. 2011;286:33981-91 pubmed publisher
Angata T, Hayakawa T, Yamanaka M, Varki A, Nakamura M. Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates. FASEB J. 2006;20:1964-73 pubmed

product information

master code :

MAB1072

SKU :

MAB1072

product name :

Human Siglec-5/CD170 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human Siglec-5/CD170 Antibody from R&D Systems is a mouse monoclonal antibody to Siglec-5/CD170. This antibody reacts with bovine,human,ovine. The Human Siglec-5/CD170 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry.

target :

Siglec-5/CD170

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

194117

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Siglec-5/CD170, Lys18-Thr434, Accession # O15389

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Bovine,Human,Ovine

specificity :

Detects human Siglec-5/CD170 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Siglec-2, -3, -7, -9, or -14 is observed.

gene symbol :

SIGLEC5

accessionNumbers :

O15389

applications :

Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry

USD :

559 USD

alt names :

CD170, CD170 antigen, CD33 antigen-like 2, CD33L2, CD33L2OB binding protein-2, OBBP2, OB-BP2OB-binding protein 2, OBBP2sialic acid-binding Ig-like lectin 5, Obesity-binding protein 2, sialic acid binding Ig-like lectin 5, sialic acid-binding immunoglobulin-like lectin 5, Siglec5, SIGLEC-5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage