product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Mouse Epiregulin Antibody
catalog :
MAB1068
quantity :
500 ug (also 25 ug)
price :
549 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
189611
reactivity :
mouse
application :
ELISA, immunohistochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 4
Reference
Odell I, Steach H, Gauld S, Reinke Breen L, Karman J, Carr T, et al. Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Sci Immunol. 2022;7:eabq6691 pubmed publisher
Wan S, Sun Y, Fu J, Song H, Xiao Z, Yang Q, et al. mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation. Cell Death Dis. 2022;13:862 pubmed publisher
Dong L, Zhang R, Zhou W, Li Y, Li H, Wu H, et al. Epiregulin, epigen and betacellulin antibodies and axial elongation in young guinea pigs with lens-induced myopization. BMC Ophthalmol. 2022;22:193 pubmed publisher
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed publisher
product information
master code :
MAB1068
SKU :
MAB1068
product name :
Mouse Epiregulin Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse Epiregulin Antibody from R&D Systems is a rat monoclonal antibody to Epiregulin. This antibody reacts with guinea pig,mouse. The Mouse Epiregulin Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,In vivo assay,Neutralization,ELISA Capture (Matched Antibody Pair).
target :
Epiregulin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
189611
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse Epiregulin, Val56-Leu101, Accession # Q61521
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Guinea Pig,Mouse
specificity :
Detects mouse Epiregulin in ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human Epiregulin is observed, but no cross-reactivity with recombinant mouse (rm) Epigen, recombinant human (rh) TGF-alpha , rhAmphiregulin, rmBetacellulin, rhEGF, rhHB-EGF, rhHRG-alpha , or rhHRG┐▀ is observed. In sandwich immunoassays, no cross-reactivity with rmAmphiregulin, rhNRG-1┐▀1, rmBetacellulin, rmEGF, rhHeregulin, rhHB-EGF, or rhTGF-alpha is observed.
gene symbol :
EREG
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by Epiregulin and Neutralization by Mouse Epiregulin Antibody.
accessionNumbers :
Q61521
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,In vivo assay,Neutralization,ELISA Capture (Matched Antibody Pair)
USD :
549 USD
alt names :
epiregulin, ER, EREG, proepiregulin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.