Human NKG2A/CD159a Antibody | R&D Systems MAB1059-SP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKG2A/CD159a Antibody

catalog :

MAB1059-SP

quantity :

25 ug

price :

129 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

131411

reactivity :

human

application :

flow cytometry, other

citations: 13

Reference
Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
Pump W, Kraemer T, Huyton T, Hò G, Blasczyk R, Bade Doeding C. Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8⁺ T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia. Int J Mol Sci. 2019;20: pubmed publisher
Muller Durovic B, Grählert J, Devine O, Akbar A, Hess C. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging (Albany NY). 2019;11:724-740 pubmed publisher
Sun H, Xu J, Huang Q, Huang M, Li K, Qu K, et al. Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC. Cancer Res. 2018;78:6581-6593 pubmed publisher
Xia Y, Zhang Q, Zhen Q, Zhao Y, Liu N, Li T, et al. Negative regulation of tumor-infiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway. Oncotarget. 2017;8:37783-37795 pubmed publisher
Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, et al. WNT5A transforms intestinal CD8Î±Î±âº IELs into an unconventional phenotype with pro-inflammatory features. BMC Gastroenterol. 2015;15:173 pubmed publisher
Wang F, Zhou Y, Fu B, Wu Y, Zhang R, Sun R, et al. Molecular signatures and transcriptional regulatory networks of human immature decidual NK and mature peripheral NK cells. Eur J Immunol. 2014;44:2771-84 pubmed publisher
Serrano Pertierra E, Cernuda Morollón E, Brdicka T, Hoøejši V, Lopez Larrea C. L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration. J Leukoc Biol. 2014;96:437-45 pubmed publisher
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le V, et al. MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog. 2014;10:e1003963 pubmed publisher
Angelini D, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, et al. NKG2A inhibits NKG2C effector functions of ?? T cells: implications in health and disease. J Leukoc Biol. 2011;89:75-84 pubmed publisher
Dulphy N, Haas P, Busson M, Belhadj S, Peffault De Latour R, Robin M, et al. An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation. J Immunol. 2008;181:2227-37 pubmed
Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou J, Charreau B. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation. Blood. 2007;109:2806-14 pubmed
Brando C, Mukhopadhyay S, Kovacs E, Medina R, Patel P, Catina T, et al. Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104. J Leukoc Biol. 2005;78:359-71 pubmed

product information

brand :

R&D Systems

master code :

MAB1059

SKU :

MAB1059-SP

product name :

Human NKG2A/CD159a Antibody

description :

The Human NKG2A/CD159a Antibody from R&D Systems is a mouse monoclonal antibody to NKG2A/CD159a/KLRC1. This antibody reacts with human. The Human NKG2A/CD159a Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready.

target :

NKG2A/CD159a/KLRC1

category :

Primary Antibodies

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

131411

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

BaF3 mouse pro-B cell line transfected with human NKG2A and CD94

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.

gene symbol :

KLRC1

applications :

Flow Cytometry, CyTOF-ready

USD 2021 :

119

USD 2022 :

129 USD

alt name :

CD159 antigen-like family member A, CD159a, CD159a antigen, C-lectin type II protein, killer cell lectin-like receptor subfamily C, member 1, Klrc1, MGC13374, natural killer cell lectin, natural killer group protein 2, NK cell receptor A, NKG2, NKG2-1/B activating NK receptor, NKG2-A, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2AMGC59791, NKG2-B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.