product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human OX40 Ligand/TNFSF4 Antibody
catalog :
MAB10541-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
159403
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 8
Reference
Hwang S, Lim J, Kang H, Jeong J, Joung J, Heo J, et al. Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy. Cell Biosci. 2023;13:17 pubmed publisher
Xu N, Tse B, Yang L, Tang T, Haber M, Micklethwaite K, et al. Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy. Immunotargets Ther. 2021;10:123-140 pubmed publisher
Jacquemin C, Augusto J, Scherlinger M, Gensous N, Forcade E, Douchet I, et al. OX40L/OX40 axis impairs follicular and natural Treg function in human SLE. JCI Insight. 2018;3: pubmed publisher
Kaisar M, Ritter M, del Fresno C, Jónasdóttir H, van der Ham A, Pelgrom L, et al. Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses. PLoS Biol. 2018;16:e2005504 pubmed publisher
Laustsen J, Rasmussen T, Stengaard Pedersen K, Hørslev Petersen K, Hetland M, Østergaard M, et al. Soluble OX40L is associated with presence of autoantibodies in early rheumatoid arthritis. Arthritis Res Ther. 2014;16:474 pubmed publisher
Beynon V, Quintana F, Weiner H. Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling. PLoS ONE. 2012;7:e39576 pubmed publisher
Ribot J, deBarros A, Mancio Silva L, Pamplona A, Silva Santos B. B7-CD28 costimulatory signals control the survival and proliferation of murine and human ?? T cells via IL-2 production. J Immunol. 2012;189:1202-8 pubmed publisher
Godfrey W, Spoden D, Ge Y, Baker S, Liu B, Levine B, et al. Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood. 2005;105:750-8 pubmed
product information
brand :
R&D Systems
master code :
MAB10541
SKU :
MAB10541-100
product name :
Human OX40 Ligand/TNFSF4 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human OX40 Ligand/TNFSF4 Antibody from R&D Systems is a mouse monoclonal antibody to OX40 Ligand/TNFSF4. This antibody reacts with human. The Human OX40 Ligand/TNFSF4 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
OX40 Ligand/TNFSF4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
159403
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 2.5 ug/10^6 cells, Neutralization 0.1-0.6 ug/mL, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human OX40 Ligand, Gln51-Leu183, Accession # P23510
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human OX40 Ligand in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhCD27 Ligand, recombinant mouse (rm) CD27 Ligand, rhCD30 Ligand, rmCD30 Ligand, rhCD40 Ligand, rmEDA, rhFas Ligand, rmFas Ligand, rhGITR Ligand, recombinant cotton rat TNF-alpha , rhTNF-alpha , rmTNF-alpha , recombinant porcine TNF-alpha , recombinant rat TNF-alpha , rhTRAIL, rhTRANCE, rmTRANCE, or rhVEGF is observed.
gene symbol :
TNFSF4
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of OX40 Ligand/ TNFSF4 antibody in Human Mature Dendritic Cells antibody by Flow Cytometry.
accessionNumbers :
P23510
applications :
Flow Cytometry,Immunocytochemistry,CyTOF-ready,Immunohistochemistry,Neutralization
USD :
499 USD
alt names :
CD134 ligand, CD134L, CD252, CD252 antigen, Glycoprotein Gp34, gp34, OX40 antigen ligand, OX40 ligand, OX40L, OX-40L, OX4OL, TAX transcriptionally-activated glycoprotein 1, tax-transcriptionally activated glycoprotein 1 (34kD), tax-transcriptionally activated glycoprotein 1, 34kD, TNFSF4, tumor necrosis factor (ligand) superfamily, member 4, tumor necrosis factor ligand superfamily member 4, TXGP1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.