SARS-CoV-2 Spike S1 Subunit Antibody | R&D Systems MAB105403-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

SARS-CoV-2 Spike S1 Subunit Antibody

catalog :

MAB105403-100

quantity :

100 ug (also 25 ug)

price :

389 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1035206

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Metko M, Tonne J, Veliz Rios A, Thompson J, Mudrick H, Masopust D, et al. Intranasal Prime-Boost with Spike Vectors Generates Antibody and T-Cell Responses at the Site of SARS-CoV-2 Infection. Vaccines (Basel). 2024;12: pubmed publisher
Qing E, Gallagher T. Adaptive variations in SARS-CoV-2 spike proteins: effects on distinct virus-cell entry stages. MBio. 2023;14:e0017123 pubmed publisher
Mitchell A, Yu C, Zhao X, Pearmain L, Shah R, Hanley K, et al. Rapid Generation of Pulmonary Organoids from Induced Pluripotent Stem Cells by Co-Culturing Endodermal and Mesodermal Progenitors for Pulmonary Disease Modelling. Biomedicines. 2023;11: pubmed publisher
Erickson M, Logsdon A, Rhea E, Hansen K, Holden S, Banks W, et al. Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease. Brain Behav Immun. 2023;109:251-268 pubmed publisher
Arrindell J, Abou Atmeh P, Jayet L, Sereme Y, Mege J, Desnues B. Vimentin is an important ACE2 co-receptor for SARS-CoV-2 in epithelial cells. iScience. 2022;25:105463 pubmed publisher
Iwata Yoshikawa N, Kakizaki M, Shiwa Sudo N, Okura T, Tahara M, Fukushi S, et al. Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways. Nat Commun. 2022;13:6100 pubmed publisher
Meng B, Datir R, Choi J, Bradley J, Smith K, Lee J, et al. SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity. Cell Rep. 2022;40:111220 pubmed publisher

product information

master code :

MAB105403

SKU :

MAB105403-100

product name :

SARS-CoV-2 Spike S1 Subunit Antibody

unit size :

100 ug (also 25 ug)

description :

The SARS-CoV-2 Spike S1 Subunit Antibody from R&D Systems is a mouse monoclonal antibody to SARS-CoV-2 Spike S1 Protein. This antibody reacts with human,mouse,n/a,primate - cercopithecus aethiops (african green monkey),primate - chlorocebus aethiops (african green monkey),sars-cov-2. The SARS-CoV-2 Spike S1 Subunit Antibody has been validated for the following applications: ELISA Control,ELISA Development,Western Blot,Immunohistochemistry,In vivo assay,Flow Cytometry,CyTOF-ready.

target :

Spike S1 Subunit

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

1035206

conjugate :

Unconjugated

host :

Mouse

immunogen :

HEK293-derived SARS-CoV-2 Spike S1 Subunit protein, Accession # YP_009724390.1

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,N/A,Primate - Cercopithecus aethiops (African Green Monkey),Primate - Chlorocebus aethiops (African Green Monkey),SARS-CoV-2

specificity :

Detects SARS-CoV-2 Spike S1 subunit in direct ELISAs and Western blots. Detects SARS-CoV-2 B.1.1.529 S RBD (Omicron Variant) in direct ELISAs. No cross-reactivity with SARS-CoV-2 Spike RBD is observed in direct ELISAs or Western blots.

accessionNumbers :

YP_009724390.1

applications :

ELISA Control,ELISA Development,Western Blot,Immunohistochemistry,In vivo assay,Flow Cytometry,CyTOF-ready

USD :

389 USD

alt names :

SARS-CoV-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage