Mouse Ly-6G (Gr-1) Antibody | R&D Systems MAB10371-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Ly-6G (Gr-1) Antibody

catalog :

MAB10371-100

quantity :

100 ug (also 25 ug)

price :

409 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1A8

reactivity :

mouse

application :

immunohistochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 14

Reference
Greenman R, Snir T, Katav A, Aricha R, Mishalian I, Hay O, et al. The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data. Cells. 2024;13: pubmed publisher
Riedel J, Robben L, Paust H, Zhao Y, Asada N, Song N, et al. Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury. JCI Insight. 2023;8: pubmed publisher
Kumar A, Singh P, Ahmed Z, Singh S, Kumar A. Essential Role of NLRP3 Inflammasome in Mediating IL-1β Production and the Pathobiology of Staphylococcus aureus Endophthalmitis. Infect Immun. 2022;90:e0010322 pubmed publisher
Terasawa M, Hiramoto K, Uchida R, Suzuki K. Anti-Inflammatory Activity of Orally Administered Monostroma nitidum Rhamnan Sulfate against Lipopolysaccharide-Induced Damage to Mouse Organs and Vascular Endothelium. Mar Drugs. 2022;20: pubmed publisher
Herath K, Kim H, Kim A, Sook C, Lee B, Jee Y. The Role of Fucoidans Isolated from the Sporophylls of Undaria pinnatifida against Particulate-Matter-Induced Allergic Airway Inflammation: Evidence of the Attenuation of Oxidative Stress and Inflammatory Responses. Molecules. 2020;25: pubmed publisher
Gupta N, Singh P, Revankar S, Chandrasekar P, Kumar A. Pathobiology of Aspergillus Fumigatus Endophthalmitis in Immunocompetent and Immunocompromised Mice. Microorganisms. 2019;7: pubmed publisher
Kimmey J, Huynh J, Weiss L, Park S, Kambal A, Debnath J, et al. Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection. Nature. 2015;528:565-9 pubmed publisher
Yipp B, Kubes P. Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo. Blood. 2013;121:241-2 pubmed publisher
Jarchum I, Liu M, Shi C, Equinda M, Pamer E. Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis. Infect Immun. 2012;80:2989-96 pubmed publisher
Tate M, Ioannidis L, Croker B, Brown L, Brooks A, Reading P. The role of neutrophils during mild and severe influenza virus infections of mice. PLoS ONE. 2011;6:e17618 pubmed publisher
Wojtasiak M, Pickett D, Tate M, Londrigan S, Bedoui S, Brooks A, et al. Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection. J Gen Virol. 2010;91:2158-66 pubmed publisher
Dunay I, Fuchs A, Sibley L. Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice. Infect Immun. 2010;78:1564-70 pubmed publisher
Tate M, Deng Y, Jones J, Anderson G, Brooks A, Reading P. Neutrophils ameliorate lung injury and the development of severe disease during influenza infection. J Immunol. 2009;183:7441-50 pubmed publisher
Daley J, Thomay A, Connolly M, Reichner J, Albina J. Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol. 2008;83:64-70 pubmed

product information

master code :

MAB10371

SKU :

MAB10371-100

product name :

Mouse Ly-6G (Gr-1) Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Ly-6G (Gr-1) Antibody from R&D Systems is a rat monoclonal antibody to Ly-6G/Ly-6C. This antibody reacts with mouse,transgenic mouse. The Mouse Ly-6G (Gr-1) Antibody has been validated for the following applications: Neutrophil Depletion,Flow Cytometry,Neutralization,Immunohistochemistry,In vivo assay,CyTOF-ready.

target :

Ly-6G (Gr-1)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

1A8

conjugate :

Unconjugated

host :

Rat

immunogen :

Ly-6G transfected EL-4J cell line, Accession # P35461

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Ly-6G in Flow Cytometry.

top caption :

Detection of Ly-6G (GR-1) antibody in Mouse Bone Marrow Cells antibody by Flow Cytometry

accessionNumbers :

P35461

applications :

Neutrophil Depletion,Flow Cytometry,Neutralization,Immunohistochemistry,In vivo assay,CyTOF-ready

USD :

409 USD

alt names :

GR, Gr1, Gr-1, Ly-6, Ly6G

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage