Human B7-H3 Antibody | R&D Systems MAB1027 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-H3 Antibody

catalog :

MAB1027

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

185504

reactivity :

human

application :

western blot, flow cytometry

citations: 5

Reference
Sucker A, Zhao F, Real B, Heeke C, Bielefeld N, MaÎ²en S, et al. Genetic evolution of T-cell resistance in the course of melanoma progression. Clin Cancer Res. 2014;20:6593-604 pubmed publisher
Ramsay A, Clear A, Fatah R, Gribben J. Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood. 2012;120:1412-21 pubmed publisher
Crispen P, Sheinin Y, Roth T, Lohse C, Kuntz S, Frigola X, et al. Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clin Cancer Res. 2008;14:5150-7 pubmed publisher
Tran C, Thacker S, Louie D, Oliver J, White P, Endres J, et al. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol. 2008;180:2989-98 pubmed
Das S, Suarez G, Beswick E, Sierra J, Graham D, Reyes V. Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection. J Immunol. 2006;176:3000-9 pubmed

product information

brand :

R&D Systems

master code :

MAB1027

SKU :

MAB1027-100

product name :

Human B7-H3 Antibody

description :

The Human B7-H3 Antibody from R&D Systems is a mouse monoclonal antibody to B7-H3/CD276. This antibody reacts with human. The Human B7-H3 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, CyTOF-ready, Knockout Validated.

target :

B7-H3/CD276

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

185504

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human B7-H3, Leu29-Pro245, Accession # NP_079516

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human B7-H3 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) B7-H1, rhB7-H2, rhB7-1, rhB7-2, or recombinant mouse PD-L2 is observed.

gene symbol :

CD276

details of functionality :

ActivityAssaywCitation not found None None None

catalog number base :

MAB1027

accessionNumbers :

NP_079516

applications :

Western Blot, Flow Cytometry, CyTOF-ready, Knockout Validated

2020 USD :

339

2021 USD :

369 USD

alt names :

B7H3, B7H34Ig-B7-H3, B7-H3B7 homolog 3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.