Human CD25/IL-2R alpha Antibody | R&D Systems MAB1020 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD25/IL-2R alpha Antibody

catalog :

MAB1020

quantity :

500 ug (also 25 ug)

price :

589 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

24212

reactivity :

human, dogs

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Shankar S, Stolp J, Juvet S, Beckett J, Macklin P, Issa F, et al. Ex vivo-expanded human CD19+TIM-1+ regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis. Nat Commun. 2022;13:3121 pubmed publisher
McEwen A, Maher M, Mo R, Gottardi C. E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion. Mol Biol Cell. 2014;25:2365-74 pubmed publisher
Ndhlovu L, Leal F, Eccles James I, Jha A, Lanteri M, Norris P, et al. A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties. Eur J Immunol. 2010;40:134-41 pubmed publisher
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
Voo K, Peng G, Guo Z, Fu T, Li Y, Frappier L, et al. Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation. Cancer Res. 2005;65:1577-86 pubmed

product information

master code :

MAB1020

SKU :

MAB1020

product name :

Human CD25/IL-2R alpha Antibody

unit size :

500 ug (also 25 ug)

description :

The Human CD25/IL-2R alpha Antibody from R&D Systems is a mouse monoclonal antibody to CD25/IL-2R alpha. This antibody reacts with canine,human. The Human CD25/IL-2R alpha Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunocytochemistry,Western Blot,Blockade of Receptor-ligand Interaction,CyTOF-ready.

target :

CD25/IL-2R alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

24212

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD25/IL-2 R alpha , Glu22-Cys213, Accession # P01589

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Canine,Human

specificity :

Detects human CD25/IL-2 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R gamma or rhIL-15 R alpha is observed.

gene symbol :

IL2RA

top caption :

IL-2 binding to Human CD25/IL-2R alpha-transfected HEK293 Human Cell Line is Blocked by Human CD25/IL-2R alpha Antibody.

accessionNumbers :

P01589

applications :

Flow Cytometry,Neutralization,Immunocytochemistry,Western Blot,Blockade of Receptor-ligand Interaction,CyTOF-ready

USD :

589 USD

alt names :

CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage