product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human UNC5H3 Antibody
catalog :
MAB1005
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
200414
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
  • immunocytochemistry; human
  • western blot; human
Wetzel Smith M, Hunkapiller J, Bhangale T, Srinivasan K, Maloney J, Atwal J, et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nat Med. 2014;20:1452-7 pubmed publisher
Wu J, Wang G, He B, Chen X, An Y. Methylation of the UNC5C gene and its protein expression in colorectal cancer. Tumour Biol. 2017;39:1010428317697564 pubmed publisher
Coissieux M, Tomsic J, Castets M, Hampel H, Tuupanen S, Andrieu N, et al. Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer. Gastroenterology. 2011;141:2039-46 pubmed publisher
product information
master code :
MAB1005
SKU :
MAB1005
product name :
Human UNC5H3 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human UNC5H3 Antibody from R&D Systems is a mouse monoclonal antibody to UNC5H3/UNC5C. This antibody reacts with human. The Human UNC5H3 Antibody has been validated for the following applications: Immunohistochemistry-Paraffin,Immunohistochemistry,Western Blot.
target :
UNC5H3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
200414
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human UNC5H3, Ala40-Asp376, Accession # O95185
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human UNC5H3 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human UNC5H4 or recombinant rat UNC5H2 is observed.
gene symbol :
UNC5C
accessionNumbers :
O95185
applications :
Immunohistochemistry-Paraffin,Immunohistochemistry,Western Blot
USD :
559 USD
alt names :
netrin receptor UNC5C, Protein unc-5 homolog 3, Protein unc-5 homolog C, unc-5 homolog 3, unc-5 homolog C (C. elegans), UNC5C, UNC5H3unc5 (C.elegans homolog) c
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.