product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse ST2/IL-33R Antibody
catalog :
MAB10041-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
489 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
245707
reactivity :
human, mouse
application :
ELISA, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
Tan J, Wei J, Lu H. sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis. Inflammation. 2023;46:1305-1317 pubmed publisher
Wang L, Luo Y, Luo L, Wu D, Ding X, Zheng H, et al. Adiponectin restrains ILC2 activation by AMPK-mediated feedback inhibition of IL-33 signaling. J Exp Med. 2021;218: pubmed publisher
Huang J, Gandini M, Chen L, M Dahoma S, Stemkowski P, Chung H, et al. Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk. Cell Rep. 2020;33:108233 pubmed publisher
He Z, Song J, Hua J, Yang M, Ma Y, Yu T, et al. Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colons. Cell Death Dis. 2018;9:1173 pubmed publisher
Walker M, Green J, Ferrie R, Queener A, Kaplan M, Cook Mills J. Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation. J Allergy Clin Immunol. 2018;141:1711-1725.e9 pubmed publisher
Ito Y, Schaefer N, Sánchez A, Francisco D, Alam R, Martin R, et al. Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice. J Innate Immun. 2018;10:106-118 pubmed publisher
Liu B, Tai Y, Achanta S, Kaelberer M, Caceres A, Shao X, et al. IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy. Proc Natl Acad Sci U S A. 2016;113:E7572-E7579 pubmed
Kumamoto Y, Linehan M, Weinstein J, Laidlaw B, Craft J, Iwasaki A. CD301b? dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 2013;39:733-43 pubmed publisher
Monticelli L, Sonnenberg G, Abt M, Alenghat T, Ziegler C, Doering T, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011;12:1045-54 pubmed publisher
Ohno T, Oboki K, Morita H, Kajiwara N, Arae K, Tanaka S, et al. Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation. PLoS ONE. 2011;6:e18404 pubmed publisher
Miller A, Asquith D, Hueber A, Anderson L, Holmes W, McKenzie A, et al. Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circ Res. 2010;107:650-8 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB10041
SKU :
MAB10041-100
product name :
Mouse ST2/IL-33R Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse ST2/IL-33R Antibody from R&D Systems is a rat monoclonal antibody to ST2/IL-33R. This antibody reacts with mouse. The Mouse ST2/IL-33R Antibody has been validated for the following applications: Flow Cytometry,Neutralization,In vivo assay,ELISA Capture (Matched Antibody Pair),CyTOF-ready.
target :
ST2/IL-33R
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
245707
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, Neutralization 0.5-3 ug/mL, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Rat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse ST2/IL-33 R, Ser27-Arg332, Accession # P14719
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse ST2/IL-33 R in ELISAs.
gene symbol :
Il1rl1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of ST2/IL-33 R antibody in P815 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
P14719
applications :
ELISA Capture (Matched Antibody Pair),CyTOF-ready,Flow Cytometry,In vivo assay,Neutralization
USD :
489 USD
alt names :
DER4, DER4ST2growth stimulation-expressed, FIT-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33 R, IL33R, IL-33R, interleukin 1 receptor-like 1, interleukin 1 receptor-related protein, interleukin-1 receptor-like 1, Ly84, MGC32623, Protein ST2, ST2L, ST2V, T1, T1homolog of mouse growth stimulation-expressed
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.