product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CD3 epsilon Antibody
catalog :
MAB100-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 70
Reference
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Ruan M, Thorn K, Liu S, Li S, Yang W, Zhang C, et al. The secretion of IL-6 by CpG-ODN-treated cancer cells promotes T-cell immune responses partly through the TLR-9/AP-1 pathway in oral squamous cell carcinoma. Int J Oncol. 2014;44:2103-10 pubmed publisher
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Eikawa S, Ohue Y, Kitaoka K, Aji T, Uenaka A, Oka M, et al. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. J Immunol. 2010;185:6734-40 pubmed publisher
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product information
brand :
R&D Systems
master code :
MAB100
SKU :
MAB100-100
product name :
Human CD3 epsilon Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human CD3 epsilon Antibody from R&D Systems is a mouse monoclonal antibody to CD3 epsilon. This antibody reacts with feline,human,mouse,primate. The Human CD3 epsilon Antibody has been validated for the following applications: Immunocytochemistry,Bioassay,Binding Assay,ELISA Development,Stimulation,T Cell Activation,Tissue Culture,Flow Cytometry,Immunoprecipitation,Functional Assay,Cell Culture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot,T Cell Stimulation,CyTOF-reported.
target :
CD3 epsilon
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
UCHT1
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation, T Cell Stimulation, Immunocytochemistry 8-25 ug/mL, CyTOF-reported
host :
Mouse
immunogen :
Human thymocytes (1),
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Feline,Human,Mouse,Primate
specificity :
Recognizes the epsilon -chain of the CD3/T cell antigen receptor complex (McMichael, A.J. et al . (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, New York; Knapp, W. et al . (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York; Schlossman, S. et al . (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York).
gene symbol :
CD3E
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
CD3e antibody in Human PBMCs by Immunocytochemistry (ICC).
applications :
Western Blot,T Cell Stimulation,CyTOF-reported,Bioassay,Binding Assay,ELISA Development,Stimulation,T Cell Activation,Tissue Culture,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Functional Assay,Cell Culture
extended description :
Clone UCHT1 was used by HLDA to establish CD designation
USD :
469 USD
product details :
Clone UCHT1 was used by HLDA to establish CD designation
alt names :
CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.