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company name :
R&D Systems
product type :
antibody
product name :
Human CD3 epsilon Antibody
catalog :
MAB100-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 70
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Yuan Y, Zhou C, Yuan J, Liu L, Guo X, Wang X, et al. NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells. Oncol Lett. 2016;12:3167-3174 pubmed
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Witte K, Gruetz G, Volk H, Looman A, Asadullah K, Sterry W, et al. Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun. 2009;10:702-14 pubmed publisher
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Tran C, Thacker S, Louie D, Oliver J, White P, Endres J, et al. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol. 2008;180:2989-98 pubmed
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McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, et al. Preferential migration of T regulatory cells induced by IL-16. J Immunol. 2007;179:6439-45 pubmed
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Rossol M, Meusch U, Pierer M, Kaltenhäuser S, Hantzschel H, Hauschildt S, et al. Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells. J Immunol. 2007;179:4239-48 pubmed
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Stebbings R, Findlay L, Edwards C, Eastwood D, Bird C, North D, et al. "Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol. 2007;179:3325-31 pubmed
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Bayry J, Triebel F, Kaveri S, Tough D. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol. 2007;178:4184-93 pubmed
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Mamoni R, Blotta M. Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis. Cytokine. 2006;35:207-16 pubmed
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Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux N, et al. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol. 2006;169:987-98 pubmed
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Markovic S, Nevala W, Uhl C, Celis E, McKean D. A reproducible method for the enumeration of functional (cytokine producing) versus non-functional peptide-specific cytotoxic T lymphocytes in human peripheral blood. Clin Exp Immunol. 2006;145:438-47 pubmed
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Ren Y, Lin C, Li Z, Chen X, Huang X, Lui V, et al. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Histopathology. 2005;46:659-67 pubmed
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Ogilvie R, Abelson M, Hau H, Vlasova I, Blackshear P, Bohjanen P. Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J Immunol. 2005;174:953-61 pubmed
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Liao T, Yurgelun M, Chang S, Zhang H, Murakami K, Blaine T, et al. Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone. J Orthop Res. 2005;23:203-9 pubmed
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Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity. 2004;21:241-54 pubmed
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Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung T, et al. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem J. 2004;380:425-33 pubmed
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Janardhan A, Swigut T, Hill B, Myers M, Skowronski J. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol. 2004;2:E6 pubmed
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Takahashi R, Mizukawa Y, Yamazaki Y, Hayakawa K, Hayakawa J, Kudo A, et al. In vitro differentiation from naive to mature E-selectin binding CD4 T cells: acquisition of skin-homing properties occurs independently of cutaneous lymphocyte antigen expression. J Immunol. 2003;171:5769-77 pubmed
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Han M, Kim J, Park B, Kim J, Hwang B, Lee H, et al. NF-kappaB-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: potential role in rheumatoid arthritis. J Leukoc Biol. 2003;73:525-9 pubmed
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product information
brand :
R&D Systems
master code :
MAB100
SKU :
MAB100-100
product name :
Human CD3 epsilon Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human CD3 epsilon Antibody from R&D Systems is a mouse monoclonal antibody to CD3 epsilon. This antibody reacts with feline,human,mouse,primate. The Human CD3 epsilon Antibody has been validated for the following applications: Immunocytochemistry,Bioassay,Binding Assay,ELISA Development,Stimulation,T Cell Activation,Tissue Culture,Flow Cytometry,Immunoprecipitation,Functional Assay,Cell Culture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot,T Cell Stimulation,CyTOF-reported.
target :
CD3 epsilon
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
UCHT1
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation, T Cell Stimulation, Immunocytochemistry 8-25 ug/mL, CyTOF-reported
host :
Mouse
immunogen :
Human thymocytes (1),
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Feline,Human,Mouse,Primate
specificity :
Recognizes the epsilon -chain of the CD3/T cell antigen receptor complex (McMichael, A.J. et al . (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, New York; Knapp, W. et al . (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York; Schlossman, S. et al . (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York).
gene symbol :
CD3E
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
CD3e antibody in Human PBMCs by Immunocytochemistry (ICC).
applications :
Western Blot,T Cell Stimulation,CyTOF-reported,Bioassay,Binding Assay,ELISA Development,Stimulation,T Cell Activation,Tissue Culture,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Functional Assay,Cell Culture
extended description :
Clone UCHT1 was used by HLDA to establish CD designation
USD :
469 USD
product details :
Clone UCHT1 was used by HLDA to establish CD designation
alt names :
CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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