product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Angiopoietin-2 Antibody
catalog :
MAB0983-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
180102
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 9
Reference
Keller S, Kunz U, Schmid U, Beusmans J, B xfc chert M, He M, et al. Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor. J Transl Med. 2024;22:934 pubmed publisher
Kim B, Jang C, Dharaneeswaran H, Li J, Bhide M, Yang S, et al. Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest. 2018;128:4543-4556 pubmed publisher
Demolli S, Doddaballapur A, Devraj K, Stark K, Manavski Y, Eckart A, et al. Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D. Cardiovasc Res. 2017;113:681-691 pubmed publisher
Choi H, Zhang H, Park H, Choi K, Lee H, Agrawal V, et al. Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2. Nat Commun. 2015;6:6943 pubmed publisher
Maffei R, Fiorcari S, Bulgarelli J, Martinelli S, Castelli I, Deaglio S, et al. Physical contact with endothelial cells through ?1- and ?2- integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells. Haematologica. 2012;97:952-60 pubmed publisher
Maffei R, Martinelli S, Santachiara R, Rossi D, Guarnotta C, Sozzi E, et al. Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia. Blood. 2010;116:584-92 pubmed publisher
Mofarrahi M, Nouh T, Qureshi S, Guillot L, Mayaki D, Hussain S. Regulation of angiopoietin expression by bacterial lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol. 2008;294:L955-63 pubmed publisher
Choo Wing R, Nedrelow J, Homer R, Elias J, Bhandari V. Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007;293:L142-50 pubmed
Tseng J, Hsu S, Ho E, Hsieh Y, Wen M, Chou M. Differential expression of angiopoietin-1, angiopoietin-2, and Tie receptors in placentas from pregnancies complicated by placenta accreta. Am J Obstet Gynecol. 2006;194:564-71 pubmed
product information
master code :
MAB0983
SKU :
MAB0983-100
product name :
Human Angiopoietin-2 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human Angiopoietin-2 Antibody from R&D Systems is a mouse monoclonal antibody to Angiopoietin-2. This antibody reacts with human,mouse. The Human Angiopoietin-2 Antibody has been validated for the following applications: ELISA Detection,Western Blot,Immunohistochemistry-Paraffin.
target :
Angiopoietin-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
180102
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Angiopoietin-2, Asp68-Phe496, Accession # O15123
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human Angiopoietin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) Ang-1, rhAng-4, rhAng-X, or rmANGPTL3.
gene symbol :
ANGPT2
top caption :
Detection of Human Angiopoietin-2 antibody by Western Blot.
accessionNumbers :
O15123
applications :
ELISA Detection,Western Blot,Immunohistochemistry-Paraffin
USD :
489 USD
alt names :
AGPT2, ANG2, ANG-2, angiopoietin 2, angiopoietin-2, angiopoietin-2a, angiopoietin-2B, angiopoitin 2, ANGPT2, Tie2-ligand
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.