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company name :
R&D Systems
product type :
other
product name :
Rat IgG1 Isotype Control
catalog :
MAB005
quantity :
500 ug
price :
226 USD
more info or order :
citations: 57
Reference
Kwak D, Park D, Kim J. Leukotriene B4 Receptor 2 Mediates the Production of G-CSF That Plays a Critical Role in Steroid-Resistant Neutrophilic Airway Inflammation. Biomedicines. 2022;10: pubmed publisher
Paldor M, Levkovitch Siany O, Eidelshtein D, Adar R, Enk C, Marmary Y, et al. Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis. EMBO Mol Med. 2022;14:e15653 pubmed publisher
Kamei H, Ishii T, Nishii Y. Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement. Sci Rep. 2022;12:9243 pubmed publisher
Hemmers C, Schulte C, Wollenhaupt J, Wong D, Harlacher E, Orth Alampour S, et al. Chemokine CCL9 Is Upregulated Early in Chronic Kidney Disease and Counteracts Kidney Inflammation and Fibrosis. Biomedicines. 2022;10: pubmed publisher
Bruchard M, Geindreau M, Perrichet A, Truntzer C, Ballot E, Boidot R, et al. Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses. Nat Immunol. 2022;23:262-274 pubmed publisher
Suzuki S, Toyoma S, Kawasaki Y, Yamada T. Irradiated fibroblasts increase interleukin-6 expression and induce migration of head and neck squamous cell carcinoma. PLoS ONE. 2022;17:e0262549 pubmed publisher
Yu H, Zhang T, Lu H, Ma Q, Zhao D, Sun J, et al. Granulocyte colony-stimulating factor (G-CSF) mediates bone resorption in periodontitis. BMC Oral Health. 2021;21:299 pubmed publisher
Zhang M, Gao J, Zhao X, Zhao M, Ma D, Zhang X, et al. p38α in macrophages aggravates arterial endothelium injury by releasing IL-6 through phosphorylating megakaryocytic leukemia 1. Redox Biol. 2021;38:101775 pubmed publisher
Brown R, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma -, Todt D, et al. Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Sci Adv. 2020;6: pubmed publisher
Mulfaul K, Ozaki E, Fernando N, Brennan K, Chirco K, Connolly E, et al. Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration. Cell Rep. 2020;30:2209-2224.e5 pubmed publisher
Yu M, Malik Tyagi A, Li J, Adams J, Denning T, Weitzmann M, et al. PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells. Nat Commun. 2020;11:468 pubmed publisher
Takagaki Y, Lee S, Dongqing Z, Kitada M, Kanasaki K, Koya D. Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis. Autophagy. 2020;:1-10 pubmed publisher
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed publisher
Das M, Tang X, Han J, Mayilsamy K, Foran E, Biswal M, et al. CCL20-CCR6 axis modulated traumatic brain injury-induced visual pathologies. J Neuroinflammation. 2019;16:115 pubmed publisher
Spalinger M, Schmidt T, Schwarzfischer M, Hering L, Atrott K, Lang S, et al. Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner. J Clin Invest. 2019;129:2527-2541 pubmed publisher
John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed publisher
Ubellacker J, Baryawno N, Severe N, Decristo M, Sceneay J, Hutchinson J, et al. Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer. Cancer Res. 2018;78:5300-5314 pubmed publisher
Hoh B, Rojas K, Lin L, Fazal H, Hourani S, Nowicki K, et al. Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin. J Am Heart Assoc. 2018;7: pubmed publisher
Mita Y, Nakayama K, Inari S, Nishito Y, Yoshioka Y, Sakai N, et al. Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models. Nat Commun. 2017;8:1658 pubmed publisher
Zhang J, Yao W, Dong C, Yang C, Ren Q, Ma M, et al. Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut-microbiota-brain axis. Transl Psychiatry. 2017;7:e1138 pubmed publisher
Banuelos J, Cao Y, Shin S, Bochner B, Avila P, Li S, et al. Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils. PLoS ONE. 2017;12:e0177884 pubmed publisher
Viladomiu M, Bassaganya Riera J, Tubau Juni N, Kronsteiner B, Leber A, Philipson C, et al. Cooperation of Gastric Mononuclear Phagocytes with Helicobacter pylori during Colonization. J Immunol. 2017;198:3195-3204 pubmed publisher
Schock S, Chandra N, Sun Y, Irie T, Kitagawa Y, Gotoh B, et al. Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway. Cell Death Differ. 2017;24:615-625 pubmed publisher
Krebs C, Paust H, Krohn S, Koyro T, Brix S, Riedel J, et al. Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney. Immunity. 2016;45:1078-1092 pubmed publisher
Prasad S, Starck S, Shastri N. Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli. J Immunol. 2016;197:2981-2991 pubmed
Caetano M, Zhang H, Cumpian A, Gong L, Unver N, Ostrin E, et al. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Res. 2016;76:3189-99 pubmed publisher
Bohannon J, Luan L, Hernandez A, Afzal A, Guo Y, Patil N, et al. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. J Leukoc Biol. 2016;99:629-40 pubmed publisher
Sotoodehnejadnematalahi F, Staples K, Chrysanthou E, Pearson H, Ziegler Heitbrock L, Burke B. Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages. PLoS ONE. 2015;10:e0125799 pubmed publisher
Agarwal S, Lakoma A, Chen Z, Hicks J, Metelitsa L, Kim E, et al. G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation. Cancer Res. 2015;75:2566-79 pubmed publisher
Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency. J Immunol. 2015;194:5407-16 pubmed publisher
Chandler R, Damrauer J, Raab J, Schisler J, Wilkerson M, Didion J, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. 2015;6:6118 pubmed publisher
Levy O, Calippe B, Lavalette S, Hu S, Raoul W, Dominguez E, et al. Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration. EMBO Mol Med. 2015;7:211-26 pubmed publisher
McKelvey R, Berta T, Old E, Ji R, Fitzgerald M. Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. J Neurosci. 2015;35:457-66 pubmed publisher
Brooks R, Iyer S, Akada H, Neelam S, Russo C, Chisholm J, et al. Coordinate expansion of murine hematopoietic and mesenchymal stem cell compartments by SHIPi. Stem Cells. 2015;33:848-58 pubmed publisher
Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, et al. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature. 2014;515:130-3 pubmed publisher
Kowalewska P, Patrick A, Fox Robichaud A. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. PLoS ONE. 2014;9:e104537 pubmed publisher
Klein M, Brouwer M, Angele B, Geldhoff M, Marquez G, Varona R, et al. Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis. PLoS ONE. 2014;9:e93057 pubmed publisher
Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, et al. The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck. PLoS Pathog. 2014;10:e1004026 pubmed publisher
Picco G, Beatson R, Taylor Papadimitriou J, Burchell J. Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas. Eur J Immunol. 2014;44:1947-55 pubmed publisher
Ramkhelawon B, Hennessy E, Ménager M, Ray T, Sheedy F, Hutchison S, et al. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med. 2014;20:377-84 pubmed publisher
Gardner J, Noel J, Nikolaidis N, Karns R, Aronow B, Ogle C, et al. G-CSF drives a posttraumatic immune program that protects the host from infection. J Immunol. 2014;192:2405-17 pubmed publisher
Bhargava R, Altmann C, Andres Hernando A, Webb R, Okamura K, Yang Y, et al. Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-? antibodies. PLoS ONE. 2013;8:e79037 pubmed publisher
Yokota Nakatsuma A, Takeuchi H, Ohoka Y, Kato C, Song S, Hoshino T, et al. Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells. Mucosal Immunol. 2014;7:786-801 pubmed publisher
Kim M, Gorouhi F, Ramirez S, Granick J, Byrne B, Soulika A, et al. Catecholamine stress alters neutrophil trafficking and impairs wound healing by ?2-adrenergic receptor-mediated upregulation of IL-6. J Invest Dermatol. 2014;134:809-817 pubmed publisher
Kulkarni S, Singh P, Ghosh S, Posarac A, Singh V. Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. Cytokine. 2013;62:278-85 pubmed publisher
Mabuchi T, Singh T, Takekoshi T, Jia G, Wu X, Kao M, et al. CCR6 is required for epidermal trafficking of γδ-T cells in an IL-23-induced model of psoriasiform dermatitis. J Invest Dermatol. 2013;133:164-71 pubmed publisher
Blotta S, Jakubikova J, Calimeri T, Roccaro A, Amodio N, Azab A, et al. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma. Blood. 2012;120:5002-13 pubmed publisher
Waight J, Hu Q, Miller A, Liu S, Abrams S. Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism. PLoS ONE. 2011;6:e27690 pubmed publisher
Kempf T, Zarbock A, Widera C, Butz S, Stadtmann A, Rossaint J, et al. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat Med. 2011;17:581-8 pubmed publisher
Humrich J, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, et al. Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. Proc Natl Acad Sci U S A. 2010;107:204-9 pubmed publisher
Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, et al. G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc Natl Acad Sci U S A. 2009;106:6742-7 pubmed publisher
Cruickshank S, deSchoolmeester M, Svensson M, Howell G, Bazakou A, Logunova L, et al. Rapid dendritic cell mobilization to the large intestinal epithelium is associated with resistance to Trichuris muris infection. J Immunol. 2009;182:3055-62 pubmed publisher
Ye F, Yan S, Xu L, Jiang Z, Liu N, Xiong S, et al. Tr1 regulatory T cells induced by ConA pretreatment prevent mice from ConA-induced hepatitis. Immunol Lett. 2009;122:198-207 pubmed publisher
Smith E, Zarbock A, Stark M, Burcin T, Bruce A, Foley P, et al. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. J Immunol. 2007;179:8274-9 pubmed
Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T. Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice. Eur J Immunol. 2007;37:2753-63 pubmed
Ludwig R, Zollner T, Santoso S, Hardt K, Gille J, Baatz H, et al. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. J Invest Dermatol. 2005;125:969-76 pubmed
Okamatsu Y, Kim D, Battaglino R, Sasaki H, Späte U, Stashenko P. MIP-1 gamma promotes receptor-activator-of-NF-kappa-B-ligand-induced osteoclast formation and survival. J Immunol. 2004;173:2084-90 pubmed
image
image 1 :
R&D Systems MAB005 image 1
Detection of Rat IgG Isotype Control by Flow Cytometry
product information
brand :
R&D Systems
master code :
MAB005
SKU :
MAB005
product name :
Rat IgG1 Isotype Control
description :
The Rat IgG1 Isotype Control from R&D Systems is a rat monoclonal control for IgG1. This control reacts with rat. The Rat IgG1 Isotype Control has been validated for the following applications: Control.
target :
IgG1
category :
Isotype Controls
unit sizes :
500 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.
clonality :
Monoclonal
clone :
43414
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
KLH
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Rat
specificity :
Selected for use as rat IgG1 isotype control. In direct ELISAs, no cross-react with recombinant human (rh) 6Ckine, recombinant mouse (rm) 6Ckine, rhACT II (rhMIP-1 beta ), rhBLC/BCA-1, rmC10, recombinant rat (rr) CINC-1, rrCINC-2 alpha , rrCINC-2 beta , rmCRG-2, rhENA-78, rhEotaxin, rmEotaxin, rhEotaxin 2, rhFractalkine, rmFractalkine, rhGCP-2, rmGCP-2, rhGRO alpha , rhGRO beta , rhGRO gamma , rhHCC-1, rhHCC-4, rhI-309, rhIL-8, rhIL-16, rhIP-10, rmJE, rmKC, rmLymphotactin, rmMARC, rhMCP-1, rhMCP-1 R, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha , rmMIP-1 alpha , rmMIP-1 beta , rmMIP-1 gamma , rhMIP-1 delta , rmMIP-2, rhMIP-3 alpha , rrMIP-3 alpha , rhMIP-3 beta , rmMIP-3 beta , recombinant viral (rv) MIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhParc, rhRANTES, rmRANTES, rhSDF-1 alpha , rmSDF-1 alpha , rhSDF-1 beta , rhTarc, rmTCA-3, rhTeck, or rmTeck.
gene symbol :
IGHG1
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
applications :
Control
USD :
226 USD
alt names :
IgG1, Igh-4, RGD1359539, VH7183
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.